A new non-invasive test for kidney disease, developed by clinicians at Hammersmith Hospitals NHS Trust and Imperial College London, is providing a simple, safe, cheap and reliable method of detecting kidney disease. The new test, reported today in the journal Nephrology Dialysis Transplantation, can detect disease before symptoms become apparent, and offers a quicker way of finding out if patients are responding to treatment – which could mean that some patients might not need costly dialysis.
Around 100,000 people in the UK have kidney disease, and the number is increasing, costing the NHS over £2 billion annually. Over 7000 people die from kidney failure every year. “Patients with a progressive kidney disease due to vasculitis* often develop kidney failure, the only treatment for which is dialysis or kidney transplant,” explains Dr Fred Tam, consultant nephrologist at Charing Cross and Hammersmith Hospitals and senior lecturer at Imperial College London. “By looking at a chemical produced when the kidney becomes inflamed, we can test patient’s urine for the level of disease, often before clinical symptoms appear.” The test could eventually replace the need to take biopsies from the kidney – a complicated and uncomfortable surgical procedure.
Current treatments for kidney vasculitis involve using drugs that knock out the body’s immune system. These drugs can cause side effects, including vulnerability to infection and risk of reduced fertility. This new test can accurately measure response to treatment, allowing clinicians to tailor treatments to individual patients. “The test can tell us if a treatment is working, and shows us, before it is too late, if we need to change the medication, without the need to perform a biopsy,” adds Dr Tam.
Simon Wilde | alfa
Spread of deadly eye cancer halted in cells and animals
13.11.2018 | Johns Hopkins Medicine
Breakthrough in understanding how deadly pneumococcus avoids immune defenses
13.11.2018 | University of Liverpool
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
13.11.2018 | Life Sciences
13.11.2018 | Life Sciences
13.11.2018 | Awards Funding