A rapid test that can be performed during surgery to determine if melanoma has spread to lymph nodes has been developed at the Medical College of Wisconsin. The reagent making this possible has been standardized at the Medical College and is called the “MCW Melanoma Cocktail”. The test is capable of detecting even very few melanoma cells, a significant factor in managing the disease. The test for cancer spread may spare a patient an additional operation.
Melanoma is the most deadly of skin cancers and is dramatically on the rise in the United States. According to the American Cancer Society, an estimated 55,100 new cases of melanoma will develop in 2004, with 7,910 deaths. Overall, the incidence has doubled in the past 20 years.
The “MCW Melanoma Cocktail” is used for immunostaining and detecting melanoma cells in ‘sentinel lymph nodes’ during surgery, explains lead investigator Vinod Shidham, M. D., FIAC, MRCPath, associate professor in the department of pathology and executive editor and editor-in-chief of CytoJournal. Dr. Shidham is also director of the Fine Needle Aspiration Biopsy Service at Froedtert Hospital, a major teaching hospital of the Medical College. The study’s co-investigators at the Medical College were Walter Dzwierzynski, M. D., associate professor of plastic surgery, and Marcelle Neuburg, M.D., associate professor of dermatology. Both physicians practice at Froedtert Hospital.
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19.03.2019 | Karl-Franzens-Universität Graz
DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.
The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...
Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.
The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...
Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.
Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...
The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.
A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...
Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.
"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...
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22.03.2019 | Life Sciences
22.03.2019 | Life Sciences
22.03.2019 | Information Technology