A Mayo Clinic research team is focusing on a hormone previously identified in the venom of the green mamba snake for the role it may play in a dangerous blood vessel narrowing in stroke patients that can lead to a second stroke, reduced blood flow and brain damage.
Called “cerebral vasospasm,” this common complication of stroke occurs in approximately one-third of patients who experience a ruptured brain blood vessel. Its cause is not known. By discovering a possible role for this hormone, Mayo Clinic researchers are establishing the conceptual foundations for a new treatment for cerebral vasospasm. Their report occurs in the current issue of Neurosurgery.
In their pilot study, the Mayo Clinic researchers discovered that a specific pair of amino acids -- a “peptide” known as DNP -- was significantly elevated (29 percent) in aneurysm patients who went on to develop complications of cerebral vasospasm. Among the six patients in the study who were followed for seven days after their initial aneurysm ruptured, four patients showed evidence of cerebral vasospasm -- a much higher frequency than the 30 percent figure commonly cited. Of the four patients who had cerebral vasospasm, three -- 75 percent -- had increased DNP levels.
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
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New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
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Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
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17.08.2018 | Life Sciences
17.08.2018 | Event News
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