Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Simple Blood Test Will Help Diabetic Patients Avoid Leg Amputation

30.07.2004


A simple blood test can now predict the probability of success for a procedure that can save the lower leg of diabetic patients facing amputation according to a study presented at the American Orthopaedic Foot and Ankle Society’s (AOFAS) annual meeting today.



The study, conducted by Alastair Younger, M.D. and Colin Meakin, M.D. at St. Paul’s Hospital in Vancouver, British Columbia, examined 21 patients with diabetes who received successful partial foot amputations and 21 diabetic patients who experienced a failed amputation. Those with a 7% or lower level of glucose in their blood had a high rate of success with a partial foot amputation and did not need a blow knee amputation (BKA).

When a diabetic patient shows signs of having a foot ulcer - which is an open wound on the bottom of the foot - doctors first try to heal it using a variety of methods. If those methods fail, the ulcers become severe and often infected, causing many doctors to quickly perform a below knee amputation. This results in a patients’ loss of mobility and independence.


An alternative to a BKA is a transmetatarsal amputation (TMA) in which the front portion of the foot containing the ulcer is removed. TMAs have a 75% success rate, but for the 25% of patients whose TMA’s fail, the process of getting another corrective surgery is monetarily, physically, and mentally taxing. This failure rate has caused many surgeons to skip an attempt at a TMA and simply perform a BKA.

However, foot amputation success can now be at least partially predicted. According to Dr. Younger, “the number one important aspect in the success of a TMA is the quality of diabetic control.” When a diabetic patient is said to be in control, they have taken good care in stabilizing their blood sugar levels. Also, diabetic patients who do not smoke have a much higher success rate for a TMA.

Diabetic control can be measured by a test called a HBA 1C, which measures a diabetic’s glucose level in the blood for past three months. This gives doctors an indication of how well a diabetic patient is taking care of their condition. The lower the percentage of glucose in the blood, the higher the rate of success of a TMA. “When glucose is greater than 10% of the blood, the TMA is bound to fail, but when it is below 7% the rate of success is high, and a surgeon should perform a TMA,” said Dr. Younger.

Another improvement on the operation involves a new invention, called Osteoset Beads. These small beads get inserted into the foot after partial amputation to release antibiotics, helping to prevent infection and speed recovery of a patient. “When doctors can save a limb, they should perform that surgery under the right conditions,” noted Dr. Meakin.

With these new discoveries, “we can save more limbs than were able to in the past,” said Dr. Younger. Dr.’s Younger and Meakin hope that orthopaedic surgeons will now consider performing a TMA instead of a BKA to help diabetic patients maintain their mobility and sense of independence.

The AOFAS is the leading professional organization for orthopaedic surgeons specializing in disorders of the foot and ankle. Orthopaedic surgeons are medical doctors with extensive training in the diagnosis and treatment of the musculoskeletal system that includes bones, joints, ligaments, tendons, muscles, and nerves.

| newswise
Further information:
http://www.aofas.org

More articles from Health and Medicine:

nachricht Nitric oxide-scavenging hydrogel developed for rheumatoid arthritis treatment
06.06.2019 | Pohang University of Science & Technology (POSTECH)

nachricht Infants later diagnosed with autism follow adults’ gaze, but seldom initiate joint attention
24.05.2019 | Schwedischer Forschungsrat - The Swedish Research Council

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The hidden structure of the periodic system

The well-known representation of chemical elements is just one example of how objects can be arranged and classified

The periodic table of elements that most chemistry books depict is only one special case. This tabular overview of the chemical elements, which goes back to...

Im Focus: MPSD team discovers light-induced ferroelectricity in strontium titanate

Light can be used not only to measure materials’ properties, but also to change them. Especially interesting are those cases in which the function of a material can be modified, such as its ability to conduct electricity or to store information in its magnetic state. A team led by Andrea Cavalleri from the Max Planck Institute for the Structure and Dynamics of Matter in Hamburg used terahertz frequency light pulses to transform a non-ferroelectric material into a ferroelectric one.

Ferroelectricity is a state in which the constituent lattice “looks” in one specific direction, forming a macroscopic electrical polarisation. The ability to...

Im Focus: Determining the Earth’s gravity field more accurately than ever before

Researchers at TU Graz calculate the most accurate gravity field determination of the Earth using 1.16 billion satellite measurements. This yields valuable knowledge for climate research.

The Earth’s gravity fluctuates from place to place. Geodesists use this phenomenon to observe geodynamic and climatological processes. Using...

Im Focus: Tube anemone has the largest animal mitochondrial genome ever sequenced

Discovery by Brazilian and US researchers could change the classification of two species, which appear more akin to jellyfish than was thought.

The tube anemone Isarachnanthus nocturnus is only 15 cm long but has the largest mitochondrial genome of any animal sequenced to date, with 80,923 base pairs....

Im Focus: Tiny light box opens new doors into the nanoworld

Researchers at Chalmers University of Technology, Sweden, have discovered a completely new way of capturing, amplifying and linking light to matter at the nanolevel. Using a tiny box, built from stacked atomically thin material, they have succeeded in creating a type of feedback loop in which light and matter become one. The discovery, which was recently published in Nature Nanotechnology, opens up new possibilities in the world of nanophotonics.

Photonics is concerned with various means of using light. Fibre-optic communication is an example of photonics, as is the technology behind photodetectors and...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

 
Latest News

Uncovering hidden protein structures

18.06.2019 | Life Sciences

Monitoring biodiversity with sound: how machines can enrich our knowledge

18.06.2019 | Life Sciences

Schizophrenia: Adolescence is the game-changer

18.06.2019 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>