For nearly a decade, scientists have known that leptin plays an important fat-burning role in humans. But the map of leptins path through the body – the key to understanding how and why the hormone works – is still incomplete.
Now a small but critical section of that map is charted, based on new research conducted at Brown Medical School and Rhode Island Hospital and at Harvard Medical School and Beth Israel Deaconess Medical Center.
The research team found that leptin triggers production of the active form of a peptide – áMSH – in the hypothalamus, the small area in the base of the brain that controls hunger and metabolism. Researchers say this peptide, or small protein, is one of the bodys most powerful metabolism booster signals, sending a fast, strong message to the brain to burn calories.
Wendy Lawton | EurekAlert!
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