Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Innovative ‘self healing’ bandage to help diabetics

25.05.2004


A revolutionary type of ‘self healing’ bandage that uses the patient’s own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers. The bandages are already available for patients with severe burns.



The bandages have been developed by CellTran Ltd., a spin-out company from the University of Sheffield. CellTran has grown from fundamental research funded by the Engineering and Physical Sciences Research Council (EPSRC).

Levels of diabetes in the UK are forecast to rise significantly in the years ahead. Chronic ulcers affect many diabetics, with sufferers often attending clinics for months or years to have their wounds dressed. CellTran offers an innovative but simple approach to healing diabetic ulcers and other slow-healing wounds, based on a combination of surface engineering and cell biology.


A small tissue sample is taken from a patient and a culture is grown from the cells in a laboratory. The cells are then placed on a membrane made from a medical-grade polymer. The membrane has been treated with a special cell-friendly coating, enabling skin cells to attach and grow on this surface. When cells are ready, the cell-membrane bandage is taken to the relevant clinic and used to dress the patient’s wound instead of a standard bandage.

Because these cells belong to the patient, they are not rejected by the body but can actually transfer to the wound and grow. For particularly difficult wounds, the cells are applied every week. Early clinical studies have shown that weekly dressings enable these difficult wounds to heal in an average of eight weeks. Clinical trials are now under way, and the technique is also being used on other types of ulcer and on patients with extensive burns.

The underlying EPSRC-funded work at the University has focused on the development of surfaces that human cells will not only grow on but also transfer from to the patient’s wound. It is also developing new approaches to culturing human skin cells without using animal derived products such as bovine serum.

The new bandages could take some pressure off healthcare budgets by reducing the need for long-term patient treatment. CellTran also aims to develop off-the-shelf products which can be used in the patient’s home, avoiding visits to outpatient clinics altogether. Sheila MacNeil, CellTran’s Research & Development Director and Professor of Tissue Engineering at the University of Sheffield, says; “we are moving the technology through to clinical use as quickly as we can and our objective is to make it as simple to use and as low-cost as possible”.

Jane Reck | alfa
Further information:
http://www.epsrc.ac.uk

More articles from Health and Medicine:

nachricht Remdesivir prevents MERS coronavirus disease in monkeys
14.02.2020 | NIH/National Institute of Allergy and Infectious Diseases

nachricht Recent advances in addressing tuberculosis give hope for future
12.02.2020 | NIH/National Institute of Allergy and Infectious Diseases

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Skyrmions like it hot: Spin structures are controllable even at high temperatures

Investigation of the temperature dependence of the skyrmion Hall effect reveals further insights into possible new data storage devices

The joint research project of Johannes Gutenberg University Mainz (JGU) and the Massachusetts Institute of Technology (MIT) that had previously demonstrated...

Im Focus: Making the internet more energy efficient through systemic optimization

Researchers at Chalmers University of Technology, Sweden, recently completed a 5-year research project looking at how to make fibre optic communications systems more energy efficient. Among their proposals are smart, error-correcting data chip circuits, which they refined to be 10 times less energy consumptive. The project has yielded several scientific articles, in publications including Nature Communications.

Streaming films and music, scrolling through social media, and using cloud-based storage services are everyday activities now.

Im Focus: New synthesis methods enhance 3D chemical space for drug discovery

After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery. Nature Catalysis published their most recent work -- a streamlined process for making a three-dimensional scaffold of keen interest to the pharmaceutical industry.

"Our tools open up whole new chemical space for potential drug targets," says Huw Davies, Emory professor of organic chemistry and senior author of the paper.

Im Focus: Quantum fluctuations sustain the record superconductor

Superconductivity approaching room temperature may be possible in hydrogen-rich compounds at much lower pressures than previously expected

Reaching room-temperature superconductivity is one of the biggest dreams in physics. Its discovery would bring a technological revolution by providing...

Im Focus: New coronavirus module in SORMAS

HZI-developed app for disease control is expanded to stop the spread of the pathogen

At the end of December 2019, the first cases of pneumonia caused by a novel coronavirus were reported from the Chinese city of Wuhan. Since then, infections...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

70th Lindau Nobel Laureate Meeting: Around 70 Laureates set to meet with young scientists from approx. 100 countries

12.02.2020 | Event News

11th Advanced Battery Power Conference, March 24-25, 2020 in Münster/Germany

16.01.2020 | Event News

Laser Colloquium Hydrogen LKH2: fast and reliable fuel cell manufacturing

15.01.2020 | Event News

 
Latest News

Electric solid propellant -- can it take the heat?

14.02.2020 | Physics and Astronomy

Pitt study uncovers new electronic state of matter

14.02.2020 | Physics and Astronomy

Researchers observe quantum interferences in real-time using a new extreme ultra-violet light spectroscopy technique

14.02.2020 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>