Two largest organ transplant societies join forces to tackle problem of traditional and exotic infections in thoracic transplantation
Complications from infectious diseases, such as HIV and West Nile virus in heart and lung transplant patients, is the focus of a joint symposium at the International Society for Heart and Lung Transplantation (ISHLT) 24th Annual Meeting held in San Francisco.
When demand for organs continually outstrips supply, offering transplants to patients with infectious diseases, such as HIV, remains controversial. For those needing heart and lung transplants, it’s not only controversial but somewhat uncharted territory. Only in the last few years have organ transplants even been offered to HIV-positive patients, much less performed; and most of the procedures have been liver and kidney transplants.
In addition to traditional viral infections, such as herpes, hepatitis C and influenza, "exotic" infections like SARS and West Nile virus are becoming a major problem for transplant recipients. These infections may have direct effects contributing to morbidity and mortality, as well as indirect effects resulting in organ dysfunction and loss.
Atul Humar, M.D. from the University of Toronto, Canada, is presenting SARS and West Nile virus as emerging infectious diseases in transplantation. Although most infections in the general population are asymptomatic, little is known about the consequences of infection in transplant recipients.
"Efforts aimed at improving our understanding of the diagnosis, natural history, prevention and treatment of these infections will lead to improved transplant organ and patient survival," said Dr. Humar.
About ISHLT The International Society for Heart and Lung Transplantation (ISHLT) is a not-for-profit organization dedicated to the advancement of the science and treatment of end-stage heart and lung diseases. Created in 1981 at a gathering of about 15 cardiologists and cardiac surgeons, the Society now includes more than 2,200 members from 45-plus countries, representing a variety of disciplines involved in the management and treatment of end-stage heart and lung disease.
ISHLT maintains two databases. The International Heart and Lung Transplant Registry is a one-of-a-kind registry that has been collecting data since 1983 from 223 hospitals from 18 countries. The ISHLT Mechanical Circulatory Device (MCSD) database has been collecting data since 2002 with the aim of identifying patient populations who may benefit from MCSD implantation; generating predictive models for outcomes; and assessing the mechanical and biological reliability of current and future devices.
Kelly Goff | EurekAlert!
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
17.08.2018 | Event News
08.08.2018 | Event News
27.07.2018 | Event News
17.08.2018 | Physics and Astronomy
17.08.2018 | Information Technology
17.08.2018 | Life Sciences