Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study evaluates various strategies for diagnosis and treatment of sore throat

07.04.2004


A comparison of various guidelines and strategies for treatment of sore throat provides information that may help optimize use of diagnostic tests and reduce unnecessary use of antibiotics, according to a study in the April 7 issue of The Journal of the American Medical Association (JAMA).



According to background information in the article, recent guidelines for management of a sore throat (pharyngitis) vary in their recommendations concerning antibiotic treatment and the need for laboratory confirmation of group A streptococcus (GAS, "strep throat"). An estimated 6.7 million health care visits are made by adults with a sore throat in the United States annually; between 1989 and 1999, 70 percent of adults presenting with sore throat received an antibiotic prescription.

Warren McIsaac, M.D., M.Sc., of Mount Sinai Hospital, Toronto, Ontario, and colleagues conducted a study to assess the impact of different clinical guidelines on the appropriateness of antibiotics prescribed, the proportion of GAS sore throat cases identified, and the use of throat cultures and rapid tests to detect GAS in a population of children and adults with a chief complaint of a sore throat.


Throat cultures and rapid antigen tests were obtained from 787 children and adults aged 3 to 69 years with acute sore throat attending a family medicine clinic in Calgary, Alberta, from September 1999 to August 2002. Recommendations from 2 guidelines (those of the Infectious Diseases Society of America [IDSA], and the American College of Physicians-American Society of Internal Medicine/American Academy of Family Physicians/U.S. Centers for Disease Control and Prevention [ASIM]) were compared with rapid testing alone, a clinical prediction rule (a clinical measurement called a Centor score), and a standard of treatment for positive throat culture results only.

The researchers found that "the selective use of throat cultures as advocated in guidelines for the management of pharyngitis is compatible with a goal of reducing overall and unnecessary use of antibiotics for treatment of pharyngitis. However, empirical antibiotic treatment of adults with a Centor score of 3 or greater as proposed in the ASIM guideline may result in 40 percent of adults being prescribed antibiotics unnecessarily. Throat cultures, or throat culture confirmation of negative rapid test results, continue to be necessary in children to ensure optimal identification of GAS pharyngitis," the authors write.

Paul Cantin | EurekAlert!
Further information:
http://www.jama.com

More articles from Health and Medicine:

nachricht Inselspital: Fewer CT scans needed after cerebral bleeding
20.03.2019 | Universitätsspital Bern

nachricht Building blocks for new medications: the University of Graz is seeking a technology partner
19.03.2019 | Karl-Franzens-Universität Graz

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

Im Focus: Revealing the secret of the vacuum for the first time

New research group at the University of Jena combines theory and experiment to demonstrate for the first time certain physical processes in a quantum vacuum

For most people, a vacuum is an empty space. Quantum physics, on the other hand, assumes that even in this lowest-energy state, particles and antiparticles...

Im Focus: Sussex scientists one step closer to a clock that could replace GPS and Galileo

Physicists in the EPic Lab at University of Sussex make crucial development in global race to develop a portable atomic clock

Scientists in the Emergent Photonics Lab (EPic Lab) at the University of Sussex have made a breakthrough to a crucial element of an atomic clock - devices...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Molecular motors run in unison in a metal-organic framework

20.03.2019 | Life Sciences

Active substance from plant slows down aggressive eye cancer

20.03.2019 | Life Sciences

Novel sensor system improves reliability of high-temperature humidity measurements

20.03.2019 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>