Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diabetes doubles risk of liver disease and liver cancer

13.02.2004


In the largest study of its kind, researchers have shown that diabetes can cause chronic liver disease and cancer of the liver. Researchers from the Department of Veterans Affairs (VA) and the National Institutes of Health report their findings in the February issue of Gastroenterology, the journal of the American Gastroenterological Association.



The prospective cohort study was comprised of 173,643 patients with diabetes and 650,620 patients without diabetes who were discharged from VA hospitals between 1985 and 1990. These patients were tracked through 2000. Most were men (98 percent). The majority (99.5 percent) of diabetic patients had type II diabetes mellitus. Among diabetic patients, the incidence of chronic liver disease and cancer of the liver was about twice the incidence that of patients without diabetes.

A link between diabetes and liver disease was previously known; it was unknown whether diabetes caused liver disease or vice versa. Liver disease associated with diabetes is usually insidious, asymptomatic and goes undetected until a severe condition, such as liver cancer, occurs.


"Because of the significantly increased risk of developing liver disease, we recommend regular testing of liver enzymes for patients with diabetes," said study author Hashem El-Serag, MD, MPH, from the Houston VA Medical Center. "For patients with diabetes who receive oral medications, there has been a concern about toxicity in the liver – more reason to test liver enzymes early on and then periodically thereafter."

The risk for developing liver disease and liver cancer is highest among patients with long-standing (10+ years since diagnosis) diabetes. The increased risk is independent of alcoholic liver disease, viral hepatitis and demographic features. The public health significance of these findings is potentially large as it is estimated that 18.2 million people in the United States have diabetes.


Gastroenterology is the official journal of the American Gastroenterological Association, the oldest non-profit specialty medical society in the United States, with a membership of more than 13,000 physicians and researchers. Gastroenterology is the most prominent journal in the subspecialty and is in the top one percent of indexed medical journals internationally. Gastroenterology is published monthly.

Jessica Willocks | EurekAlert!
Further information:
http://www.gastro.org/

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First diode for magnetic fields

Innsbruck quantum physicists have constructed a diode for magnetic fields and then tested it in the laboratory. The device, developed by the research groups led by the theorist Oriol Romero-Isart and the experimental physicist Gerhard Kirchmair, could open up a number of new applications.

Electric diodes are essential electronic components that conduct electricity in one direction but prevent conduction in the opposite one. They are found at the...

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Removing toxic mercury from contaminated water

21.11.2018 | Life Sciences

New China and US studies back use of pulse oximeters for assessing blood pressure

21.11.2018 | Medical Engineering

Exoplanet stepping stones

21.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>