Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newborn brain injuries stem from infections, not delivery

09.02.2004


Medical malpractice cases frequently try to link injuries to the white matter of a newborn’s brain -- a precursor to cerebral palsy and other disorders -- to the baby’s delivery, though a new Johns Hopkins study demonstrates that such injuries are more closely associated with neonatal infections.



White matter, the tracts of nerve fibers that communicate messages in the brain, is generally injured at so-called "end zones" between the long, penetrating arteries that supply blood to the brain. These zones are susceptible to the type of fall in cerebral blood flow and oxygen that could occur during complications in delivery, as marked by excess acid in the umbilical cord.

The Hopkins team reviewed medical records of 150 premature babies who had white matter injuries and were born between May 1994 and September 2001. They compared each baby’s delivery to that of the next healthy baby delivered at the same gestational age (23-24 weeks), looking for causes of problems.


The researchers found that acid levels in the umbilical cords were similar in both brain-injured and healthy babies, as were many other factors such as maternal infections and the percentage born by Caesarean versus vaginal delivery. The only difference noted was that brain-injured babies were more likely to have evidence of infections of the cerebrospinal fluid, blood and windpipe.

"Our study refutes the fact that white matter injuries are caused by delivery," says Ernest Graham, M.D., senior study author and assistant professor of gynecology/obstetrics. "The biggest association with these injuries in our study was clearly neonatal infections."

Graham says while you can treat the infections after birth, it’s hard to know when they originated. Also, even if the infections are treated, the babies could still be at higher risk for permanent brain damage.


Graham, Ernest et al, "Neonatal White Matter Injury is Associated with Culture Positive Infections and Only Rarely with Metabolic Acidosis."

The above news tip is based on an abstract or poster to be presented at the Society for Maternal-Fetal Medicine’s 24th Annual Meeting, held Feb. 2-7 in New Orleans.

To pursue this story, please contact Trent Stockton at 410-955-8665 or tstockt1@jhmi.edu. Please observe the embargo.

Trent Stockton | EurekAlert!
Further information:
http://www.hopkinsmedicine.org/

More articles from Health and Medicine:

nachricht When wheels and heads are spinning - DFG research project on motion sickness in automated driving
22.05.2019 | Technische Universität Berlin

nachricht A new approach to targeting cancer cells
20.05.2019 | University of California - Riverside

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Self-repairing batteries

UTokyo engineers develop a way to create high-capacity long-life batteries

Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...

Im Focus: Quantum Cloud Computing with Self-Check

With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.

Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...

Im Focus: Accelerating quantum technologies with materials processing at the atomic scale

'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.

However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...

Im Focus: A step towards probabilistic computing

Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future

When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...

Im Focus: Recording embryonic development

Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells

The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

 
Latest News

Summit charts a course to uncover the origins of genetic diseases

22.05.2019 | Life Sciences

New study finds distinct microbes living next to corals

22.05.2019 | Life Sciences

Stellar waltz with dramatic ending

22.05.2019 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>