The introduction and widespread use of highly active antiretroviral therapy (HAART) for HIV-infected persons in San Francisco in the late 1990s reduced their risks of infecting partners by 60 percent, according to a study conducted by researchers from the San Francisco Department of Public Health (SFDPH) and UCSF.
"While we found that antiretroviral use alone may account for a 60 percent reduction in risk of HIV transmission, a concurrent increase in risk behavior meant that rates of new infections did not decline sharply, but remained roughly stable for the period studied," said study lead investigator Travis Porco, PhD, MPH, an epidemiologist with SFDPH at the time the study was conducted.
The study, to be published in the January 2, 2004 issue of AIDS, analyzed data from 1994 to 1999 from the San Francisco Young Mens Health Study (YMHS), which followed young gay men who were initially uninfected with HIV. Participants were asked about their sexual practices and tested for HIV at four follow-up visits, which included two before the widespread introduction of HAART for people with HIV in San Francisco and two later visits.
Jeff Sheehy | EurekAlert!
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