Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Laser Therapy Offers Alternative to Surgery for Liver Tumours

11.09.2003


Research News in the British Journal of Surgery



11 September 2003: Laser light can be delivered in a controlled and predictable manner to destroy tumours. By inserting fibre optic cables through needles, doctors can direct the powerful laser light onto liver tumours – killing the cells and thus eliminating the need for major surgery. A review of recent research shows that this ‘interstitial laser thermotherapy’ (ITL) can be a safe and effective way of removing tumours and improving overall survival.

Cancer in the liver is extremely serious; left untreated, it can kill a person within three to twelve months of diagnosis. The best way of treating this disease is to remove the tumour by conventional surgery, but this is a major operation and is only possible in a limited number of cases.


“ITL allows a greater proportion of patients to be treated than surgery alone, but we need greater understanding of how it works if we are going to make best use of the technology,” says lead-author, M Nikfarjam, who works in the department of Surgery, at the University of Melbourne in Australia. “Advances in laser technology and refinements in techniques may allow ILT to replace surgery as the procedure of choice in selected patients with liver malignancies.”

Technical background

Lasers kill tumours because the energy contained in light particles (photons) is transformed into heat inside the cells. Heating cells to 42-45 oC for 30-60 minutes disrupts vital parts of the cells machinery (enzymes), killing the cells. Increasing the temperature decreases the amount of time needed. With temperatures of between 60oC and 140oC, cell death is almost instantaneous. Between 100 and 300 oC water in the cell vaporises, and above 300 oC the cells are burnt to carbon.

The key to success is to raise the temperature high enough to kill cells quickly, but to avoid carbonisation of the cells. If carbonisation occurs at the tip of the fibre, light is unable to penetrate the tissue. Doctors use either ultrasound scanning or magnetic resonance imaging to visualise the tumour and the fibres while they are giving the treatment.

Current research is focused on determining the optimum equipment and protocol to maximise the killing power of the laser.

Jaida Butler | alfa
Further information:
http://www.interscience.wiley.com

More articles from Health and Medicine:

nachricht Lung images of twins with asthma add to understanding of the disease
06.12.2019 | University of Western Ontario

nachricht Between Arousal and Inhibition
06.12.2019 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Developing a digital twin

University of Texas and MIT researchers create virtual UAVs that can predict vehicle health, enable autonomous decision-making

In the not too distant future, we can expect to see our skies filled with unmanned aerial vehicles (UAVs) delivering packages, maybe even people, from location...

Im Focus: The coldest reaction

With ultracold chemistry, researchers get a first look at exactly what happens during a chemical reaction

The coldest chemical reaction in the known universe took place in what appears to be a chaotic mess of lasers. The appearance deceives: Deep within that...

Im Focus: How do scars form? Fascia function as a repository of mobile scar tissue

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix. Until today, the question about the exact anatomical origin of these fibroblasts has not been answered. In order to find potential ways of influencing the scarring process, the team of Dr. Yuval Rinkevich, Group Leader for Regenerative Biology at the Institute of Lung Biology and Disease at Helmholtz Zentrum München, aimed to finally find an answer. As it was already known that all scars derive from a fibroblast lineage expressing the Engrailed-1 gene - a lineage not only present in skin, but also in fascia - the researchers intentionally tried to understand whether or not fascia might be the origin of fibroblasts.

Fibroblasts kit - ready to heal wounds

Im Focus: McMaster researcher warns plastic pollution in Great Lakes growing concern to ecosystem

Research from a leading international expert on the health of the Great Lakes suggests that the growing intensity and scale of pollution from plastics poses serious risks to human health and will continue to have profound consequences on the ecosystem.

In an article published this month in the Journal of Waste Resources and Recycling, Gail Krantzberg, a professor in the Booth School of Engineering Practice...

Im Focus: Machine learning microscope adapts lighting to improve diagnosis

Prototype microscope teaches itself the best illumination settings for diagnosing malaria

Engineers at Duke University have developed a microscope that adapts its lighting angles, colors and patterns while teaching itself the optimal...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

The Future of Work

03.12.2019 | Event News

First International Conference on Agrophotovoltaics in August 2020

15.11.2019 | Event News

Laser Symposium on Electromobility in Aachen: trends for the mobility revolution

15.11.2019 | Event News

 
Latest News

Solving the mystery of carbon on ocean floor

06.12.2019 | Earth Sciences

Chip-based optical sensor detects cancer biomarker in urine

06.12.2019 | Life Sciences

A platform for stable quantum computing, a playground for exotic physics

06.12.2019 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>