Total lymphocyte count and hemoglobin concentration lowers at onset of the disease
People with HIV and their physicians could have a less expensive tool to track the progression from HIV infection to AIDS. According to researchers from the Johns Hopkins Bloomberg School of Public Health, a decline in the total lymphocyte counts (TLC) and hemoglobin (Hgb) concentration in the blood may be used to monitor a patients disease status. Currently, HIV RNA and CD4+ cells in the blood are measured. However, specialized equipment and training for lab technicians makes these measurements expensive. TLC and Hgb measurements are much less expensive and can be obtained by using standard blood tests. "Rapid declines in total lymphocyte counts and hemoglobin concentration prior to AIDS among HIV-1-infected men," appears in the September 2003 issue of the journal AIDS, the official journal of the International AIDS Society.
The studys lead author, Bryan Lau, a graduate student in the Schools Department of Epidemiology, said, "This study demonstrates that there is a biological event that occurs during the progression of HIV infection leading to declines in TLC and Hgb within individuals. The majority of HIV individuals who develop AIDS experience a rapid decline in total lymphocyte counts and hemoglobin concentration that starts about one and one-half years prior to developing AIDS. The decline in these two markers in individuals who develop AIDS shows that this is an important event in the pathogenesis of the disease."
Kenna Brigham | EurekAlert!
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences