Lung cancer is the leading cause of cancer death in both men and women. To successfully fight the disease, doctors use a variety of techniques to diagnose the cancer and determine the extent of its spread throughout the body. When using positron emission tomography (PET) as a diagnostic tool, 18F-FDG has proven to be a reliable and accurate tracer, but false positives have been noted in areas of inflammation. Recently, German researchers conducted a study comparing the results of 18F-FDG PET and 18F-FLT PET and found the latter to be a more precise indicator for diagnosing unclear lung lesions.
The study, published in the September 2003 issue of The Journal of Nuclear Medicine, included examinations of 26 patients with pulmonary nodules revealed on chest CT. Subsequent biopsies confirmed that eighteen of the patients involved had malignant tumors, and eight had benign tumors. Using standardized uptake value (SUV), tumoral uptake was calculated for both 18F-FDG PET and 18F-FLT PET.
Results revealed 18F-FLT SUV correlated better than18F-FDG SUV with the proliferation index. This confirms the theory that 18F-FLT, a tracer specifically designed to reveal the presence of malignant tumors, is better at differentiating cancerous growths from other lesions. While the results show promise for the use of 18F-FLT, they do not indicate 18F-FLT can replace 18F-FDG, which is quite accurate in staging tumors.
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11.07.2018 | McGill University
Direct conversion of non-neuronal cells into nerve cells
03.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
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