Dale Greiner and colleagues at the University of Massachusetts have developed a protocol for achieving stem cell transplantation that is not limited by significant patient side-effects and may not necessarily require that donor blood, bone marrow or whole organs are a "match" with the recipient –- characteristics that make these new procedures highly attractive for development and use in clinical human transplantation.
Hematopoietic stem cells (HSCs) are parent cells in the bone marrow that give rise to blood cells. Allogeneic stem cell transplantation has great potential in the treatment of malignancy, genetic disorders, and in solid organ transplantation. However, the radiation or high doses of chemotherapy commonly used in the treatment of blood cancers to destroy abnormal HSCs--a process called myeloablation-- is very toxic.
Furthermore, even following this form of conditioning, many patients develop graft-versus-host disease (GVHD), where the host immune system launches an attack against the newly transplanted HSCs.
Spread of deadly eye cancer halted in cells and animals
13.11.2018 | Johns Hopkins Medicine
Breakthrough in understanding how deadly pneumococcus avoids immune defenses
13.11.2018 | University of Liverpool
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
14.11.2018 | Life Sciences
14.11.2018 | Life Sciences
14.11.2018 | Earth Sciences