A UCSF-led team has demonstrated that the cerebral cortex, the site of higher cognitive functions, not only perceives pain, but plays a role in regulating pain, and that it does so in part through the inhibitory neurotransmitter GABA, suggesting a possible target for therapy.
The finding, published in the July 17 issue of Nature, provides some of the first neuroanatomical evidence that the cerebral cortex not only receives pain signals from nerve cells in lower regions of the brain, but modulates pain signals.
"Our finding suggests that the cerebral cortex is not just the end-point of pain processing. The activity of the cortex can change the set-point of the pain threshold in a top-down manner, completely modifying the experience of pain," says lead author Luc Jasmin, MD, PhD, FRCS, UCSF assistant professor of neurological surgery.
Jennifer O’Brien | EurekAlert!
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Soft robots have a distinct advantage over their rigid forebears: they can adapt to complex environments, handle fragile objects and interact safely with humans. Made from silicone, rubber or other stretchable polymers, they are ideal for use in rehabilitation exoskeletons and robotic clothing. Soft bio-inspired robots could one day be deployed to explore remote or dangerous environments.
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Researchers at TU Graz are working together with European partners on new possibilities of measuring vehicle emissions.
Today, air pollution is one of the biggest challenges facing European cities. As part of the Horizon 2020 research project CARES (City Air Remote Emission...
Over the next three years, researchers from the Vrije Universiteit Brussel, University of Cambridge, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris (ESPCI-Paris) and Empa will be working together with the Dutch Polymer manufacturer SupraPolix on the next generation of robots: (soft) robots that ‘feel pain’ and heal themselves. The partners can count on 3 million Euro in support from the European Commission.
Soon robots will not only be found in factories and laboratories, but will be assisting us in our immediate environment. They will help us in the household, to...
Scientists at the University of Leeds have created a new form of gold which is just two atoms thick - the thinnest unsupported gold ever created.
The researchers measured the thickness of the gold to be 0.47 nanometres - that is one million times thinner than a human finger nail. The material is regarded...
An international team of scientists involving the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) in Hamburg has unraveled the light-induced electron-localization dynamics in transition metals at the attosecond timescale. The team investigated for the first time the many-body electron dynamics in transition metals before thermalization sets in. Their work has now appeared in Nature Physics.
The researchers from ETH Zurich (Switzerland), the MPSD (Germany), the Center for Computational Sciences of University of Tsukuba (Japan) and the Center for...
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