Significant genetic differences exist between tumors of the right and left side of the colon, according to data presented today at the 94th Annual Meeting of the American Association for Cancer Research (AACR), and these distinctions should be considered for future research and treatment.
"With emerging treatments directed toward specific molecular targets, there should be special emphasis on such an important differentiation," said Sanne Olesen, M.Sc. of biology, Aarhus University Hospital, Denmark, and lead investigator of the study conducted by scientists from Denmark and Finland. "Hopefully with this new understanding of the differences that exist in the colon, we can more efficiently treat cancer patients."
In the study, approximately 6,800 known genes were monitored for activity. Twenty single samples of normal colonic mucosa were compared to 25 single cancerous samples from both the left and right sides of the colon. Findings were validated by semi-quantitative, RealTime-PCR and immunohistochemistry, or observations of clinical reactions to the immune system.
Warren Froelich | EurekAlert!
A new approach to targeting cancer cells
20.05.2019 | University of California - Riverside
Radioisotope couple for tumor diagnosis and therapy
14.05.2019 | Kanazawa University
Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...
With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.
Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...
'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.
However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...
Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future
When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...
Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells
The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...
29.04.2019 | Event News
17.04.2019 | Event News
15.04.2019 | Event News
22.05.2019 | Power and Electrical Engineering
21.05.2019 | Materials Sciences
21.05.2019 | Materials Sciences