Researchers at Washington University School of Medicine in St. Louis, in collaboration with investigators at five other centers, have finished sequencing human chromosome 7. The findings are published in the July 10 issue of the journal Nature.
Chromosome 7 is the largest human chromosome to be sequenced so far. The analysis revealed that the chromosome has about 1,150 genes and 940 so-called pseudogenes, stretches of DNA that closely resemble genes but contain some genetic change that prevents them from functioning like a gene. The biological significance of pseudogenes is unknown.
"This work completes another volume in the genome encyclopedia at a high standard of quality and a high degree of continuity," says principal investigator Richard K. Wilson, Ph.D., director of Washington Universitys Genome Sequencing Center and professor of genetics and of molecular microbiology. "The sequence for chromosome 7 will be very useful for follow-up studies that have a medical application."
Darrell E. Ward | EurekAlert!
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