Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Atkins diet shows surprising results, researcher says

22.05.2003


One-year study shows diet may be as effective and safe as conventional diets



A 3-center study led by researchers at the Weight and Eating Disorders Program of the University of Pennsylvania School of Medicine reports the results of the first controlled trial of the Atkins Diet. The Atkins Diet limits carbohydrates but permits unrestricted amounts of protein and fat. Compared to a conventional, high- carbohydrate, low-calorie approach, Atkins dieters lost twice as much weight at 3 and 6 months but there was no difference between the groups at 1 year. Despite the lack of differences in weight loss at 1 year, the Atkins dieters had significantly greater increases in good cholesterol (HDL) and greater decreases in triglycerides.

The study, to be published in the May 22 issue of the New England Journal of Medicine, was led by Gary Foster, Ph.D. Associate Professor of Psychiatry and Clinical Director of the Weight and Eating Disorders Program at the University of Pennsylvania. Samuel Klein, MD of Washington University in St. Louis and James Hill, Ph.D. and Holly Wyatt, M.D. of the University of Colorado were the lead investigators at the other centers. The study investigated 63 obese men and women who were 44 years of age and weighed and average of 216 pounds.


All participants met with a registered dietitian at 0, 3, 6 and 12 months. Those in the Atkins group were given a copy of Dr. Atkins New Diet Revolution and asked to follow the diet as described. The conventional diet group was given instructional materials on a 1200-1500 calories/day (women) or 1500-1800 calories /day (men) diet that consisted of 60% carbohydrate 25% fat, and 15% protein based on the Food Guide Pyramid. Atkins participants lost an average of 14.7 pounds compared with 5.8 pounds in the conventional group at 3 months, 15.2 pounds versus 6.9 pounds at 6 months, and 9.5 versus 5.4 pounds at 12 months. At 1 year, Atkins participants had greater increases in HDL cholesterol (18% vs. 3%) and greater reductions in triglycerides (-28% vs. 1%) than did those following a conventional diet. Neither group showed changes in LDL (bad) cholesterol at 1 year .

"Obesity is a national public health problem, and we need to evaluate alternative weight loss approaches aggressively. Widely recommend low carbohydrate approaches may be premature, but our initial findings suggest that such diets may not have the adverse effects that were anticipated” Foster stated. "The real issue is whether low carbohydrate approaches help patients maintain their weight loss better than conventional approaches. It will also be important to determine whether the effects of the diet on cholesterol are the same during weight maintenance as they are they are during weight loss.” Foster also cautioned.

Results of this first, randomized, controlled study of the Atkins diet suggest that low- carbohydrate diets may not be as harmful as anticipated. "Larger and longer studies are needed to assess the long-term safety and efficacy of low carbohydrate approaches in the management of obesity. These preliminary data suggest that weight losses will be comparable to conventional approaches over a 1 year period, but there may be some favorable effects of a low-carbohydrate approach in terms of triglycerides and HDL (good) cholesterol,” Foster said.

This study was funded through grants from the National Institutes of Health (NIH) General Clinical Research Centers at the University of Pennsylvania, Washington University and the University of Colorado. Others who participated in the study at Penn were Brian McGuckin Ed.M, Research Coordinator; Philippe Szapary, MD, Assistant Professor of Medicine, and Daniel Rader, MD, Associate Professor of Medicine.

Similar findings for a low-carbohydrate diet by another group of Penn faculty working at Philadelphia VA Medical Center were also reported in the May 22 issue of the New England Journal of Medicine. In their 6-month study, Frederick Samaha, MD, and colleagues found that a low carbohydrate diet was associated with greater weight losses, reductions in triglycerides and improvements in insulin sensitivity compared to low-calorie, high-carbohydrate diet in 132 patients who were 53 years old and weighed 288 pounds.

Foster and his colleagues at the Washington University and the University of Colorado are currently enrolling participants for a large, NIH-funded, 5-year study of low- and high-carbohydrate diets.

“This larger study of 360 participants will help us more fully assess the benefits and risks of low-carbohydrate diets on bone mass, kidney function, arterial function and exercise tolerance,” Foster said.

Ellen O’Brien | EurekAlert!
Further information:
http://www.med.upenn.edu/

More articles from Health and Medicine:

nachricht Diabetes mellitus: A risk factor for early colorectal cancer
27.05.2020 | Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg

nachricht Ultra-thin fibres designed to protect nerves after brain surgery
27.05.2020 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Biotechnology: Triggered by light, a novel way to switch on an enzyme

In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme that, when illuminated with blue light, becomes catalytically active and initiates a reaction that was previously unknown in enzymatics. The study was published in "Nature Communications".

Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very...

Im Focus: New double-contrast technique picks up small tumors on MRI

Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. The work is published May 25 in the journal Nature Nanotechnology.

researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from...

Im Focus: I-call - When microimplants communicate with each other / Innovation driver digitization - "Smart Health“

Microelectronics as a key technology enables numerous innovations in the field of intelligent medical technology. The Fraunhofer Institute for Biomedical Engineering IBMT coordinates the BMBF cooperative project "I-call" realizing the first electronic system for ultrasound-based, safe and interference-resistant data transmission between implants in the human body.

When microelectronic systems are used for medical applications, they have to meet high requirements in terms of biocompatibility, reliability, energy...

Im Focus: When predictions of theoretical chemists become reality

Thomas Heine, Professor of Theoretical Chemistry at TU Dresden, together with his team, first predicted a topological 2D polymer in 2019. Only one year later, an international team led by Italian researchers was able to synthesize these materials and experimentally prove their topological properties. For the renowned journal Nature Materials, this was the occasion to invite Thomas Heine to a News and Views article, which was published this week. Under the title "Making 2D Topological Polymers a reality" Prof. Heine describes how his theory became a reality.

Ultrathin materials are extremely interesting as building blocks for next generation nano electronic devices, as it is much easier to make circuits and other...

Im Focus: Rolling into the deep

Scientists took a leukocyte as the blueprint and developed a microrobot that has the size, shape and moving capabilities of a white blood cell. Simulating a blood vessel in a laboratory setting, they succeeded in magnetically navigating the ball-shaped microroller through this dynamic and dense environment. The drug-delivery vehicle withstood the simulated blood flow, pushing the developments in targeted drug delivery a step further: inside the body, there is no better access route to all tissues and organs than the circulatory system. A robot that could actually travel through this finely woven web would revolutionize the minimally-invasive treatment of illnesses.

A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

International Coral Reef Symposium in Bremen Postponed by a Year

06.04.2020 | Event News

 
Latest News

German-British Research project for even more climate protection in the rail industry

28.05.2020 | Transportation and Logistics

A special elemental magic

28.05.2020 | Physics and Astronomy

Skoltech scientists get a sneak peek of a key process in battery 'life'

28.05.2020 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>