Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

3D mammography shows promise as next breast screening technique

08.05.2003


“Full-field digital tomosynthesis is mammography--only better,” researchers say of a new technique that just might be the next generation of breast cancer screening. Two new studies on this technique illustrate that full-field digital tomosynthesis (TOMO) can not only increase the visibility of breast lesions but could likely dramatically reduce the number of patients being called back for a second mammogram because their first screening mammogram was unclear.



In the first study, researchers compared standard plain film mammography to TOMO. Forty patients were included in the study. Radiologists detected 16 of 22 malignant lesions on mammography and 18 of 22 malignant lesions on TOMO, says Elizabeth Rafferty, MD, lead author of both studies. TOMO was superior to plain film mammography in detecting masses and architectural distortions, which results from a tethering or pulling in of the tissue, says Dr. Rafferty. Calcifications were not as conspicuous on the tomosynthesis imaging during the pilot study, she says. “We are currently implementing a solution to this challenge and will have data on this soon,” she adds.

In the second study, 45 patients were reviewed. All patients had been called back for a second mammogram because their first showed a possible abnormality; “30 of them were subsequently found by additional mammographic views to have breast tissue overlap accounting for their possible abnormality,” she says. Fifteen patients went on to biopsy. “We asked radiologists to look at the TOMO study (without knowing the results of the second mammogram or biopsy) and indicate whether they would have called these patients back for additional evaluation,” says Dr. Rafferty. They indicated that they would have only called back five of the 30 patients who had breast tissue overlap. “If we could have used TOMO on these patients initially, it would have saved 25 women the anxiety they felt and the inconvenience they experienced of being called back for additional tests,” notes Dr. Rafferty.


The radiologists indicated that they would have recalled 14 of the 15 patients who had a biopsy, says Dr. Rafferty. A single reader missed one cancer, she says. “This is well within the standard interobserver variability seen with conventional mammography,” she adds.

“TOMO allows us to take multiple projections of the breast at different angles. These projections are then reconstructed into a three-dimensional data set. We can then look at each slice individually and assess each area of the breast without confusing overlap from surrounding structures,” Dr. Rafferty says. “The ability to look at individual slices of the breast is a real asset,” she says.

TOMO is more comfortable for the patient. The patient’s breasts only need to be compressed once (compared to twice for the standard two-view mammogram); the patient sits during the procedure, and the overall radiation dose is lower, says Dr. Rafferty. Dr. Rafferty cautions, however, that “full-field digital tomosynthesis is still in its infancy.” However, she predicts, “this technique will only get better.” Researchers at Massachusetts General Hospital conceived, developed, and patented full-field breast tomosynthesis, and, in conjunction with General Electric, built the only prototype currently in clinical use. To date, more than 350 clinical tomosynthesis studies have been performed at Massachusetts General Hospital under research protocols.


Dr. Rafferty will present the results of her studies on May 8 during the American Roentgen Ray Society Annual Meeting in San Diego.

Contact: Keri J. Sperry (703) 858-4306
Danica Laub (703) 858-4332
Press Room: (619) 525-6536 (May 5-8)

Keri Sperry | EurekAlert!
Further information:
http://www.arrs.org/

More articles from Health and Medicine:

nachricht Cancer cells make blood vessels drug resistant during chemotherapy
02.07.2020 | Hokkaido University

nachricht Novel potassium channel activator which acts as a potential anticonvulsant discovered
02.07.2020 | The Mount Sinai Hospital / Mount Sinai School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electrons in the fast lane

Solar cells based on perovskite compounds could soon make electricity generation from sunlight even more efficient and cheaper. The laboratory efficiency of these perovskite solar cells already exceeds that of the well-known silicon solar cells. An international team led by Stefan Weber from the Max Planck Institute for Polymer Research (MPI-P) in Mainz has found microscopic structures in perovskite crystals that can guide the charge transport in the solar cell. Clever alignment of these "electron highways" could make perovskite solar cells even more powerful.

Solar cells convert sunlight into electricity. During this process, the electrons of the material inside the cell absorb the energy of the light....

Im Focus: The lightest electromagnetic shielding material in the world

Empa researchers have succeeded in applying aerogels to microelectronics: Aerogels based on cellulose nanofibers can effectively shield electromagnetic radiation over a wide frequency range – and they are unrivalled in terms of weight.

Electric motors and electronic devices generate electromagnetic fields that sometimes have to be shielded in order not to affect neighboring electronic...

Im Focus: Gentle wall contact – the right scenario for a fusion power plant

Quasi-continuous power exhaust developed as a wall-friendly method on ASDEX Upgrade

A promising operating mode for the plasma of a future power plant has been developed at the ASDEX Upgrade fusion device at Max Planck Institute for Plasma...

Im Focus: ILA Goes Digital – Automation & Production Technology for Adaptable Aircraft Production

Live event – July 1, 2020 - 11:00 to 11:45 (CET)
"Automation in Aerospace Industry @ Fraunhofer IFAM"

The Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM l Stade is presenting its forward-looking R&D portfolio for the first time at...

Im Focus: AI monitoring of laser welding processes - X-ray vision and eavesdropping ensure quality

With an X-ray experiment at the European Synchrotron ESRF in Grenoble (France), Empa researchers were able to demonstrate how well their real-time acoustic monitoring of laser weld seams works. With almost 90 percent reliability, they detected the formation of unwanted pores that impair the quality of weld seams. Thanks to a special evaluation method based on artificial intelligence (AI), the detection process is completed in just 70 milliseconds.

Laser welding is a process suitable for joining metals and thermoplastics. It has become particularly well established in highly automated production, for...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International conference QuApps shows status quo of quantum technology

02.07.2020 | Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

 
Latest News

Rising water temperatures could endanger the mating of many fish species

03.07.2020 | Life Sciences

Risk of infection with COVID-19 from singing: First results of aerosol study with the Bavarian Radio Chorus

03.07.2020 | Studies and Analyses

Efficient, Economical and Aesthetic: Researchers Build Electrodes from Leaves

03.07.2020 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>