Researchers at Duke University Medical Center have devised an advanced technique that uses mass spectrometry to identify specific proteins that are over-expressed in cancer cells, blood, urine, or any substance that contains proteins.
Using this new technique, they have already identified two proteins – MIF and CyP-A -- whose levels are elevated in lung cancer cells but not in normal cells, said Edward Patz, M.D., professor of radiology and pharmacology and cancer biology at Duke.
Their discovery is one of the first steps toward elucidating potential new drug targets aimed at blocking the effects of these proteins. Scientists could also develop a simple blood test using MIF and CyP-A as molecular markers to diagnose lung cancer without the need for invasive biopsies.
Becky Levine | Duke University
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New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
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Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
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17.08.2018 | Life Sciences
17.08.2018 | Event News
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