Dartmouth researchers report in the March 1 issue of Cancer Research they have discovered an effective combination therapy to treat tumors. In the journal, which is a publication of the American Association for Cancer Research, the researchers report that administering light-activated, or photodynamic, therapy (PDT) immediately before radiation therapy appears to kill tumors more effectively than just the sum of the two treatments.
"Our study shows that the close combination of the two treatments complement each other, allowing more effective therapy for the same delivered dose," says Brian Pogue, the lead author, an Associate Professor at Dartmouths Thayer School of Engineering and a Research Scientist at Harvard Medical School.
PDT is used to treat a variety of illnesses, from lung cancer to age-related blindness. The treatment uses a light-activated drug to kill tumor tissue. The drug, verteporfin in this study, is designed to accumulate within tissues with tumor-like characteristics, such as leaky vasculature and rapidly growing cells.
Sue Knapp | EurekAlert!
New flexible, transparent, wearable biopatch, improves cellular observation, drug delivery
12.11.2018 | Purdue University
Exosomes 'swarm' to protect against bacteria inhaled through the nose
12.11.2018 | Massachusetts Eye and Ear Infirmary
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
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On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
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Scientists developed specially coated nanometer-sized vehicles that can be actively moved through dense tissue like the vitreous of the eye. So far, the transport of nano-vehicles has only been demonstrated in model systems or biological fluids, but not in real tissue. The work was published in the journal Science Advances and constitutes one step further towards nanorobots becoming minimally-invasive tools for precisely delivering medicine to where it is needed.
Researchers of the “Micro, Nano and Molecular Systems” Lab at the Max Planck Institute for Intelligent Systems in Stuttgart, together with an international...
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12.11.2018 | Life Sciences
12.11.2018 | Materials Sciences
12.11.2018 | Physics and Astronomy