The timing of treatment may be a key factor in whether hormone replacement therapy (HRT) can slow heart vessel disease, report researchers from Wake Forest University Baptist Medical Center and Tufts-New England Medical Center in the winter issue of Menopausal Medicine.
"Mounting evidence points to the conclusion that HRT can help prevent heart vessel disease – if the therapy begins around the time that the body stops making its own estrogen," said Thomas B. Clarkson, D.V.M., of Wake Forest. "The question may not be if estrogen helps, but when is the optimum time to begin therapy."
Clarkson, a professor of comparative medicine, and Richard H. Karas, M.D., Ph.D., director of the preventive cardiology center at Tufts, reviewed numerous studies of postmenopausal women and monkeys that evaluated the cardiovascular effects of HRT.
Karen Richardson | EurekAlert!
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