Allowing calcium to get inside colorectal cancer cells may be one way to stop their growth.
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia knew that the same bacterial toxin that causes traveler’s diarrhea can stem the growth of metastatic colorectal cancer cells. Now, they may have found out how.
The scientists discovered that the toxin appears to open a cellular door, permitting calcium into tumor cells, which in turn somehow slows cell division. The discovery may lead to new methods of treating colorectal cancer, perhaps by combining the toxin with chemotherapy drugs and other agents.
Steve Benowitz | EurekAlert!
Further information:
http://www.tju.edu/
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