Authors of a fast-track study in this week’s issue of THE LANCET propose an alternative to antibiotics to treat infection associated with the use of chemotherapy for patients with blood cancer.
The toxic effects of chemotherapy cause organisms in the gut to migrate to the bloodstream, frequently resulting in bacterial infection. Michael Ellis and colleagues from the United Arab Emirates investigated whether interleukin 11 (IL-11)-an agent involved in the immune response and thought to protect gastrointestinal cells from toxicity associated with chemotherapy-could prevent gut-associated infections.
40 patients with blood cancer received either 50 microgrammes per kg bodyweight of IL-11 or placebo as daily injections. Significantly fewer patients who received IL-11 rather than placebo developed bacterial infection, particularly of gastrointestinal origin. IL-11 slowed the time to first infection compared with placebo
Richard Lane | alfa
Diabetes mellitus: A risk factor for early colorectal cancer
27.05.2020 | Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg
Ultra-thin fibres designed to protect nerves after brain surgery
27.05.2020 | Martin-Luther-Universität Halle-Wittenberg
In meningococci, the RNA-binding protein ProQ plays a major role. Together with RNA molecules, it regulates processes that are important for pathogenic properties of the bacteria.
Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding...
An analysis of more than 200,000 spiral galaxies has revealed unexpected links between spin directions of galaxies, and the structure formed by these links...
Two prominent X-ray emission lines of highly charged iron have puzzled astrophysicists for decades: their measured and calculated brightness ratios always disagree. This hinders good determinations of plasma temperatures and densities. New, careful high-precision measurements, together with top-level calculations now exclude all hitherto proposed explanations for this discrepancy, and thus deepen the problem.
Hot astrophysical plasmas fill the intergalactic space, and brightly shine in stellar coronae, active galactic nuclei, and supernova remnants. They contain...
In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme that, when illuminated with blue light, becomes catalytically active and initiates a reaction that was previously unknown in enzymatics. The study was published in "Nature Communications".
Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very...
Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. The work is published May 25 in the journal Nature Nanotechnology.
researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from...
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04.06.2020 | Life Sciences
04.06.2020 | Physics and Astronomy
04.06.2020 | Life Sciences