A class of drugs known as cholinesterase inhibitors has a significant impact on behavioral problems and the ability to perform everyday tasks in patients with Alzheimer’s disease, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC) and UCSF.
The study, an analysis of data from multiple small studies, appears in the January 8, 2003 issue of the Journal of the American Medical Association. Known as a meta-analysis, the study applied sophisticated statistical methods to data from 29 trials that involved the treatment of Alzheimer’s disease (AD) with cholinesterase inhibitors (ChIs).
People with AD can suffer cognitive, behavioral or functional difficulties. ChIs have been previously shown to effectively treat cognitive difficulties such as memory loss, disorientation and loss of language skills, said Kristine Yaffe, MD, Chief of Geriatric Psychiatry at the SFVAMC and UCSF assistant professor of psychiatry, neurology and epidemiology and biostatistics.
Camille Mojica Rey | EurekAlert!
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