Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Emergency Drug for Cardiac Arrest

30.09.2002


Vasopressin as an agent for cardio-pulmonary resuscitation



Diseases of the cardiovascular system continue to be the most frequent causes of death in the Western world. For over 100 years, Adrenaline has been the standard drug of choice in the treatment of sudden cardiac arrest. A team of researchers headed by Karl H. Lindner and Volker Wenzel from the University Department of Anaesthesiology and Critical Care Medicine, University of Innsbruck, has, with the support of the Austrian Science Fund (FWF) and after years of successful investigations, proved that Vasopressin is at least as successful as Adrenaline as an emergency drug used in cardio-pulmonary resuscitation.

In fact, in 2000 the findings of the Innsbruck anaesthetists led to a change in the international guidelines concerning cardio-pulmonary resuscitation. Since then, Vasopressin has been recommended as a therapy to adult patients suffering from ventricular flutter. Vasopressin improves blood pressure during cardio-pulmonary resuscitation, thus probably increasing the chances of survival of patients with cardiac arrest. As Dr. Wenzel explained, "We have detected a high dosage of endogenic Vasopressin in patients who survived a cardiac arrest. We concluded from this that the body releases more of this substance in this life-threatening situation. Our research has confirmed the assumption that Vasopressin is also of use when injected by an emergency doctor: the chances of survival within the first 24 hours after a cardiac arrest is thus increased.“


Clinical trial soon to be completed

The possible advantage of Vasopressin over Adrenaline shall now be checked on the basis of data obtained in an international clinical trial which was organised by the Innsbruck scientists and included 1219 patients in 33 emergency medical service units in Austria, Switzerland and Germany.

The results shall shortly be presented to international experts before being published in an internationally renowned magazine.

"If the data arrived at from the study meets our expectations, Vasopressin could be authorised for the treatment of patients with cardiac arrest. At present, although the international guidelines expressly recommend Vasopressin, the drug has not been officially sanctioned for such an application", Dr. Wenzel said, and he continued, "In clinical practice Vasopressin is frequently used, and several patients have benefited from its administration. However, the legal framework is somewhat lagging behind this development."

Nevertheless, among experts the achievements of the Innsbruck anaesthetists have been honoured with prizes on more than one occasion, among them the Hoechst Prize of the University of Innsbruck, the award for emergency and intensive care medicine of the universities of Munich and Munster, and prizes of the American Heart Association and the American Society of Critical Care Medicine.

Alexandra Stolba | alfa

More articles from Health and Medicine:

nachricht The FiTS app now offering cooking videos as it expands its concept for long-term behavior modification
18.09.2018 | vitaliberty GmbH

nachricht The microbiota in the intestines fuels tumour growth
18.09.2018 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Patented nanostructure for solar cells: Rough optics, smooth surface

Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.

"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...

Im Focus: New soft coral species discovered in Panama

A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.

Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...

Im Focus: New devices based on rust could reduce excess heat in computers

Physicists explore long-distance information transmission in antiferromagnetic iron oxide

Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.

Im Focus: Finding Nemo's genes

An international team of researchers has mapped Nemo's genome

An international team of researchers has mapped Nemo's genome, providing the research community with an invaluable resource to decode the response of fish to...

Im Focus: Graphene enables clock rates in the terahertz range

Graphene is considered a promising candidate for the nanoelectronics of the future. In theory, it should allow clock rates up to a thousand times faster than today’s silicon-based electronics. Scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) and the University of Duisburg-Essen (UDE), in cooperation with the Max Planck Institute for Polymer Research (MPI-P), have now shown for the first time that graphene can actually convert electronic signals with frequencies in the gigahertz range – which correspond to today’s clock rates – extremely efficiently into signals with several times higher frequency. The researchers present their results in the scientific journal “Nature”.

Graphene – an ultrathin material consisting of a single layer of interlinked carbon atoms – is considered a promising candidate for the nanoelectronics of the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

One of the world’s most prominent strategic forums for global health held in Berlin in October 2018

03.09.2018 | Event News

4th Intelligent Materials - European Symposium on Intelligent Materials

27.08.2018 | Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

 
Latest News

Making better use of enzymes: a new research project at Jacobs University

19.09.2018 | Life Sciences

Light provides spin

19.09.2018 | Physics and Astronomy

Enjoying virtual-reality-entertainment without headache or motion sickness

19.09.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>