Changes in the brains white matter may play a major role in the onset of Alzheimers disease, whose baffling origin has traditionally been blamed on the gray matter. The new findings could provide a fresh direction for Alzheimers research in this neglected part of the brain, offering the potential for early diagnosis and enhanced therapies.
The results are reported in the Sept. 17 print edition of Biochemistry, a peer-reviewed journal of the American Chemical Society, the worlds largest scientific society.
"Alzheimers disease is conventionally considered a disease of the brain gray matter because its most prominent consequence is severe memory loss," says Alex Roher, M.D., Ph.D., director of the Sun Health Research Institute in Sun City, Ariz., and lead author of the paper. The overwhelming majority of Alzheimers research has focused on gray matter, despite the fact that white matter makes up about 50 percent of total brain tissue and is substantially altered during Alzheimers progression, Roher says.
Beverly Hassell | EurekAlert!
Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
26.03.2020 | Johns Hopkins Medicine
Too much salt weakens the immune system
26.03.2020 | Rheinische Friedrich-Wilhelms-Universität Bonn
Together with their colleagues from the University of Würzburg, physicists from the group of Professor Alexander Szameit at the University of Rostock have devised a “funnel” for photons. Their discovery was recently published in the renowned journal Science and holds great promise for novel ultra-sensitive detectors as well as innovative applications in telecommunications and information processing.
The quantum-optical properties of light and its interaction with matter has fascinated the Rostock professor Alexander Szameit since College.
Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumour innervation could thus lead to new cancer therapies.
Stem cells can generate a variety of specific tissues and are increasingly used for clinical applications such as the replacement of bone or cartilage....
An international research team led by Kiel University develops an extremely porous material made of "white graphene" for new laser light applications
With a porosity of 99.99 %, it consists practically only of air, making it one of the lightest materials in the world: Aerobornitride is the name of the...
Researchers at Graz University of Technology have developed a framework by which wireless devices with different radio technologies will be able to communicate directly with each other.
Whether networked vehicles that warn of traffic jams in real time, household appliances that can be operated remotely, "wearables" that monitor physical...
Terahertz waves are becoming ever more important in science and technology. They enable us to unravel the properties of future materials, test the quality of...
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27.03.2020 | Life Sciences