OHSU study suggests that HRT may act on cancer cells to produce less aggressive tumors
A study of nearly 300 breast cancer patients at Oregon Health & Science University found that women who use hormone replacement therapy (HRT) have less aggressive tumors and are more likely to be diagnosed through mammograms than other methods. Also, HRT users with breast cancer had significantly better survival rates than non-HRT users. The study is published in the September issue of the journal The Archives of Surgery.
Because hormones increase the density of breast tissue, researchers have suspected that HRT use would make it more difficult to detect tumors on mammograms. As a result, it was suspected that tumors in patients who have received HRT might not be detected until they were larger and more advanced. However, of 144 study patients using HRT, 84 had their tumors detected by mammogram, while 60 were detected by other methods. Comparatively, of 148 non-HRT users, 63 had their tumors detected by mammogram, while 85 were detected by palpation (feeling for lumps).
Martin Munguia | EurekAlert!
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