Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New endovascular prosthesis is promising for non-surgical treatment of TAAs

06.08.2002


Research study shows promising results for non-surgical treatment of life threatening condition



Rodney White, MD, Chief of Vascular Surgery and Associate Chair, Department of Surgery at Harbor-UCLA Medical Center and Principal Investigator at the Research & Education Institute at Harbor-UCLA Medical Center (REI) is shedding new light on endovascular treatment of thoracic aortic aneurysms (TAAs). A life threatening condition caused by a weakening of the vascular wall of the aorta in the chest, TAAs can lead to either sudden death or death in a matter of hours if the aorta ruptures.

In an REI clinical study, Dr. White and a team of cardiovascular surgeons, radiologists and scientists have successfully treated approximately 60 patients over the last three years with thoracic aortic aneurysms, aortic dissections and other cause of acute rupture. REI and the Harbor-UCLA Medical Center hold the distinction of being the only study site in the Los Angeles area to conduct this FDA-approved Investigational Device Exemption (IDE) research. Results on the first 25 patients in this study were published in the Journal of Vascular Surgery, May 2001. Dr. White and his team are a part of a nationwide referral network that has also implanted endovascular prostheses into approximately 600 patients diagnosed with abdominal aortic aneurysms, the 13th leading cause of death in the United States.


Dr. White, a graduate of the State University of New York Upstate Medical Center, believes that this research holds much promise.

"With the development of endovascular prostheses to treat abdominal aortic aneurysms in the mid 1990’s, a concomitant effort to adapt this technology to the treatment of thoracic aneurysms has demonstrated promising preliminary results with a decrease in both major morbidity and mortality being noted in many patients," he says.

The new technology also makes repair of thoracic aortic aneurysms and dissections available to patients who are not considered to be reasonable candidates for conventional surgical repair. "Although the experience is preliminary, the magnitude of the conventional surgical procedure and the decreased incidence of morbidity and mortality with endovascular repairs support further evaluation of this technology," he adds.



The Research & Education Institute at Harbor-UCLA Medical Center, located on the campus of Harbor-UCLA Medical Center near Torrance, California, is a leading independent, not-for-profit biomedical research institute with an international reputation for scientific discovery, the training of physician-scientists and the provision of community service programs. It is an affiliate of both the David Geffen School of Medicine at UCLA and the Harbor-UCLA Medical Center and has an annual budget of $58 million. The Institute traces its roots back to 1952, when researchers and physicians joined forces with the UCLA School of Medicine on the campus of what was then known as Harbor General Hospital to conduct a handful of research studies. Today, more than 1,000 research projects and clinical trials are being conducted at REI, advancing scientific understanding in order to improve medical outcomes and promote innovation in such areas as autoimmune disorders, cancer, cardiovascular disease, developmental disorders and other pediatric health problems, diabetes, infectious disease, inherited disorders, male contraception, vaccine evaluation and research, and various aspects of women’s health.


Barbara T. Kerr | EurekAlert!
Further information:
http://www.rei.edu/

More articles from Health and Medicine:

nachricht Uncuffing nitric oxide production: Beta-arrestin2 complexes regulate NO levels
05.06.2020 | Medical University of South Carolina

nachricht Diabetes mellitus: A risk factor for early colorectal cancer
27.05.2020 | Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Restoring vision by gene therapy

Latest scientific findings give hope for people with incurable retinal degeneration

Humans rely dominantly on their eyesight. Losing vision means not being able to read, recognize faces or find objects. Macular degeneration is one of the major...

Im Focus: Small Protein, Big Impact

In meningococci, the RNA-binding protein ProQ plays a major role. Together with RNA molecules, it regulates processes that are important for pathogenic properties of the bacteria.

Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding...

Im Focus: K-State study reveals asymmetry in spin directions of galaxies

Research also suggests the early universe could have been spinning

An analysis of more than 200,000 spiral galaxies has revealed unexpected links between spin directions of galaxies, and the structure formed by these links...

Im Focus: New measurement exacerbates old problem

Two prominent X-ray emission lines of highly charged iron have puzzled astrophysicists for decades: their measured and calculated brightness ratios always disagree. This hinders good determinations of plasma temperatures and densities. New, careful high-precision measurements, together with top-level calculations now exclude all hitherto proposed explanations for this discrepancy, and thus deepen the problem.

Hot astrophysical plasmas fill the intergalactic space, and brightly shine in stellar coronae, active galactic nuclei, and supernova remnants. They contain...

Im Focus: Biotechnology: Triggered by light, a novel way to switch on an enzyme

In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme that, when illuminated with blue light, becomes catalytically active and initiates a reaction that was previously unknown in enzymatics. The study was published in "Nature Communications".

Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

International Coral Reef Symposium in Bremen Postponed by a Year

06.04.2020 | Event News

 
Latest News

New image of a cancer-related enzyme in action helps explain gene regulation

05.06.2020 | Life Sciences

Silicon 'neurons' may add a new dimension to computer processors

05.06.2020 | Physics and Astronomy

Protecting the Neuronal Architecture

05.06.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>