In a study led by Dr Saverio Stranges, Associate Professor of Cardiovascular Epidemiology at Warwick Medical School, the team looked at levels of oxidative stress in the body (a toxic effect which causes cell damage).
They found high levels of oxidative stress in people with coronary heart disease, previously thought to be a marker of the heart condition, could instead indicate a condition of glucose abnormality, such as overt type 2 diabetes.
The research team took blood samples to contrast oxidative stress levels in people with coronary heart disease, people with type 2 diabetes and healthy control subjects. Previous studies have shown people with type 2 diabetes and people with coronary heart disease have high levels of oxidative stress.
Dr Stranges’ team expected to produce similar results, but they found that those stress levels were low in people with coronary heart disease but without type 2 diabetes. Further investigation showed people from this group with high levels also had overt type 2 diabetes.
The research used data taken from the Western New York Health Study. This was a case-control study of myocardial infarction and cardiovascular risk factors among residents of Erie and Niagara Counties, New York.
Dr Stranges said: “The results were intriguing. We expected to find high levels of oxidative stress in people with a clinical heart condition, such as myocardial infarction, and people with diabetes. As we thought, the levels were high for diabetics, but there were some discrepancies for people with heart disease.
“Our findings suggest the observed associations of increased oxidative stress in individuals with heart disease may be dependent on underlying abnormalities in glucose metabolism.”
Additional contributors to the study were Dr Joan Dorn, Professor Richard Donahue, Professor Jo Freudenheim, Kathleen Hovey and Professor Maurizio Trevisan from the Department of Social and Preventive Medicine, State University of New York at Buffalo, NY, USA; Dr Richard Browne from the Department of Biotechnical and Clinical Laboratory Sciences, State University of New York at Buffalo, NY, USA.
Kelly Parkes-Harrison | alfa
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences