Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

6 of every 100 patients die in hospital due to adverse drug reaction

08.07.2008
Six of every 100 patients who die in hospital do so as a consequence of an adverse drug reaction or, in other words, a fatal reaction to medicines.

Those are the conclusions of a research carried out at the Department of Medicine of the University of Granada, in collaboration with the Clinical Hospital San Cecilio of Granada, by Alfredo José Pardo Cabello and directed by Professors Emilio Puche Cañas (Department of Pharmacology) and Francisco Javier Gómez Jiménez (Department of Medicine).

A adverse drug reaction to medicines (ADR) has been defined as any harmful and unwanted effect of a drug, at doses used for prophylaxis, diagnose or treatment. Their repercussion is usually minimal, but sometimes, they can be serious and they can even endanger the patient’s life.

In order to carry out this work, they analysed the clinical case history of 289 patients older than 18 who died in hospital in 2004, revising their history, the drugs they were administered, as well as data about the treatment and the death certificate. Their analysis concluded that the most frequent ADR are the digestive haemorrhages followed by intra-cranial haemorrhages and cardiac arrhythmias.

Most frequent drugs
The work carried out at the UGR has revealed that the drugs which provoked an ADR usually were AINE (medicines with a strong anti-inflammatory, analgesic and antipyretic effect) as well as platelet anti-aggregants, such as acetylsalicylic acid, two types of drugs frequently used in the daily medical practice.

Pardo Cabello has also proved the convenience of avoiding the mixing of gastro-damaging drugs such as NSAIDs, anti-aggregants and corticoids, as 53% of the deaths caused by ADR analyzed in this study had received a mixing of such medicines.

The author of this work has highlighted that, in the light of the obtained results, it is necessary to create a better awareness among the sanitary staff about adverse drug reactions and to be on the alert in the face of the slightest symptom. The research work carried out at the UGR is a completely pioneer in Spain and the results obtained coincide with those of other similar studies carried out in USA and Finland.

Reference
Alfredo José Pardo Cabello. Department of Medicine of the University of Granada.
Tel: +34 958244054.
E-mail: apardoc05@yahoo.es

Antonio Marín Ruiz | alfa
Further information:
http://www.ugr.es
http://prensa.ugr.es/prensa/research/verNota/prensa.php?nota=529

More articles from Health and Medicine:

nachricht Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University

nachricht Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>