Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sorafenib, first pharmaceutical drug to improve survival amongst patients with advanced hepatocarcinoma

27.06.2008
International research involving the University Hospital of the University of Navarra, together with other hospitals in Spain, has shown that Sorafenib, an orally administered pharmaceutical medicine, results in patients with primary hepatocarcinomas (liver tumours) to live 40% more on average compared to those not taking the drug.

The study, led by the Barcelona Hospital Clinic, will be shortly published in the New England Journal of Medicine.

This was one of the conclusions of a scientific meeting, organised by the University Hospital of Navarra in Pamplona, which dealt with novelties in the systematic treatment of hepatocarcinoma. Doctor Ruth Vera García, Head of the Oncological Medicine Service at the Hospital of Navarra, Doctor Javier Bustamante Schneider of the Digestive System Service at Cruces Hospital in Bilbao and Doctors Mercedes Iñarrairaegui Bastarrica and Bruno Sangro Gómez-Acebo, both from the Hepatology Unit of the University Hospital of Navarra, presented novelties in the systematic treatment of hepatocarcinoma. The medics coincided in emphasising that the complexity of these patients, often suffering from hepatic cirrhosis also, means that the disorder has to be approached in a multidisciplinary manner and treated at centres which have all possible treatment resources available.

The fifth most common tumour

Hepatocarcinoma is the most frequent hepatic tumour, fifth in overall worldwide cancer rates and the third cause of cancer deaths in the world. In Spain, as in the rest of Mediterranean Europe, some 10 cases per one hundred thousand inhabitants appear every year – a rate of about 500 cases in Spain annually (50 in Navarre). In more than half the cases local curative treatment such as surgery, transplant or percutaneous ablation; or palliative ones, such as arterial embolisation or radioembolisation with radioactive spheres, can be applied.

In the rest of the cases, the prognosis is not good but, in the last five years, there have appeared more than ten pharmaceutical medicines known as biological agents or directed pharmaceutical drugs, the use of which in this tumour is currently being actively investigated, giving rise to a real hope for these patients.

Of these pharmaceutical medicines, Sorafenib has been the first to demonstrate its efficacy and the European Medicines Agency has recently authorised its use for this tumour, given that it can prolong patient survival at the cost of some side effects which, in 80% of cases, are manageable with a number of preventative or therapeutic measures.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Berri_Kod=1805&hizk=I

More articles from Health and Medicine:

nachricht New nanomedicine slips through the cracks
24.04.2019 | University of Tokyo

nachricht Sugar entering the brain during septic shock causes memory loss
23.04.2019 | Rensselaer Polytechnic Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unprecedented insight into two-dimensional magnets using diamond quantum sensors

For the first time, physicists at the University of Basel have succeeded in measuring the magnetic properties of atomically thin van der Waals materials on the nanoscale. They used diamond quantum sensors to determine the strength of the magnetization of individual atomic layers of the material chromium triiodide. In addition, they found a long-sought explanation for the unusual magnetic properties of the material. The journal Science has published the findings.

The use of atomically thin, two-dimensional van der Waals materials promises innovations in numerous fields in science and technology. Scientists around the...

Im Focus: Full speed ahead for SmartEEs at Automotive Interiors Expo 2019

Flexible, organic and printed electronics conquer everyday life. The forecasts for growth promise increasing markets and opportunities for the industry. In Europe, top institutions and companies are engaged in research and further development of these technologies for tomorrow's markets and applications. However, access by SMEs is difficult. The European project SmartEEs - Smart Emerging Electronics Servicing works on the establishment of a European innovation network, which supports both the access to competences as well as the support of the enterprises with the assumption of innovations and the progress up to the commercialization.

It surrounds us and almost unconsciously accompanies us through everyday life - printed electronics. It starts with smart labels or RFID tags in clothing, we...

Im Focus: Energy-saving new LED phosphor

The human eye is particularly sensitive to green, but less sensitive to blue and red. Chemists led by Hubert Huppertz at the University of Innsbruck have now developed a new red phosphor whose light is well perceived by the eye. This increases the light yield of white LEDs by around one sixth, which can significantly improve the energy efficiency of lighting systems.

Light emitting diodes or LEDs are only able to produce light of a certain colour. However, white light can be created using different colour mixing processes.

Im Focus: Quantum gas turns supersolid

Researchers led by Francesca Ferlaino from the University of Innsbruck and the Austrian Academy of Sciences report in Physical Review X on the observation of supersolid behavior in dipolar quantum gases of erbium and dysprosium. In the dysprosium gas these properties are unprecedentedly long-lived. This sets the stage for future investigations into the nature of this exotic phase of matter.

Supersolidity is a paradoxical state where the matter is both crystallized and superfluid. Predicted 50 years ago, such a counter-intuitive phase, featuring...

Im Focus: Explosion on Jupiter-sized star 10 times more powerful than ever seen on our sun

A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter

  • Coolest and smallest star to produce a superflare found
  • Star is a tenth of the radius of our Sun
  • Researchers led by University of Warwick could only see...
All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

Fraunhofer FHR at the IEEE Radar Conference 2019 in Boston, USA

09.04.2019 | Event News

 
Latest News

Researchers discover surprising quantum effect in hard disk drive material

26.04.2019 | Physics and Astronomy

Hopkins researchers ID neurotransmitter that helps cancers progress

26.04.2019 | Life Sciences

Unprecedented insight into two-dimensional magnets using diamond quantum sensors

26.04.2019 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>