The study reveals that the fears associated with the RHT are product of disinformation and are often against clinical evidences. Some of those concerns are fear of collateral effects such as weight gain, breast cancer or the risk of a thromboembolic disease.
The passing of time makes ovaries lose their ability to produce estrogens and progesterone, the hormones which regulate the menstrual cycle. In this stage, when menstruation cesses, there appear physical and psychical changes such as hot flushes, sweating, vaginal dryness, articulation and bone pain, headaches, insomnia, sadness, depression and loss of memory, known as climateric symptoms. In Spain, the average age for the cessation of the menstrual cycle is 50 years old. In the Western countries, about 17% of the population belongs to the post-menstrual group.
Against the discomfort derived from the cessation of menstruation, there are medical treatments which contribute to maintain the quality of life of women in the face of the described changes. One of the treatments proposed is the so-called Replacement Hormone Therapy (RHT).
Fears about this therapy have been erroneously exaggerated, attributing to it secondary effects such as weight gain, breast cancer and risk of a thromboembolic disease.
A study carried out at the University of Granada on more than 500 postmenopausal patients rationalizes the fears above mentioned; and it concludes recommending the use of the hormone therapy, if necessary, for at least five years, under periodic medical controls.
The research work has been read as a doctoral thesis by Dr Otilia Ruth González Vanegas, under the supervision of Dr José Luis Cuadros López and Dr Rosa María Sabatel López (Department of Medicine of the UGR, San Cecilio University Hospital) and Dr Ángela María Cuadros Celorrio (Hospital of Úbeda).The work, entitled “Five-year later assessment of the use of different models of Replacement Hormone Therapy (RHT) during post-menopause”, started from the question: “¿how long must RHT be used considering the beneficial and adverse effects?”. They studied the clinical histories of 534 women who, between 1989 and 2004, have attended periodically medical, laboratory and mammography tests at the Menopause Unit of the San Cecilio teaching Hospital of Granada.
González Vanegas’ study also concludes that the discomfort derived from menopause falls in the first six months of application of any of the RHT, with the consequent improvement in women’s quality of life.
The observations allow to conclude that, regardless the type of hormone therapy followed, the symptomatology improves, there are no weight changes, the lipid profile improves (cholesterol, triglycerides); bone quality gets better and breast cancer is less frequent than in general population, especially in the group which only received estrogens.
The results of this research work have been published in journals such as Climateric or Menopausia.
Antonio Marín Ruiz | alfa
Collagen nanofibrils in mammalian tissues get stronger with exercise
14.12.2018 | University of Illinois College of Engineering
New discoveries predict ability to forecast dementia from single molecule
12.12.2018 | UT Southwestern Medical Center
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
14.12.2018 | Power and Electrical Engineering
14.12.2018 | Physics and Astronomy
14.12.2018 | Physics and Astronomy