Scientists at the Research & Education Institute at Harbor-UCLA Medical Center (REI) are developing a new breast imaging diagnostic tool which will afford clinicians greater opportunities for detecting early stage breast cancers with greater certainty and help patients avoid biopsy in some cases. This detection method identifies breast lesions utilizing a radiopharmaceutical diagnostic imaging technology known as Tc-99 Sestamibi (MIBI) scintimammography. The procedure is based on a radioactive isotope being injected into a vein in the arm. Once absorbed into the body, the isotope can be seen by a group of special detectors, called gamma cameras, "marking" certain biological processes to locate a tumor.
Iraj Khalkhali, MD, principal investigator at REI, believes that the number of false negative (i.e., missed tumors) readings could be reduced if the limitations of contemporary gamma cameras were overcome. In one of his studies, Dr. Khalkhali found that three out of four false negatives were in the middle part of the breast and out of range of close camera contact. Dr. Khalkhali is currently pursuing research on improving scintimammography image quality through the design and development of a compact, thin gamma camera that affords easier access to all nodes and potential breast lesion sites.
"Access to breast lesions in the internal quadrants is especially important because these tumors may disseminate toward the internal mammary chain even when no axillary node is invaded. Easy access to all nodes and potential breast lesion sites will improve image quality and can be expected to improve the diagnostic accuracy of scintimammography, " said Dr. Khalkhali. "Although mammography is currently the standard early diagnostic screening tool, scintimammography has proven to be a highly effective adjunct in identifying lesions missed by mammography – particularly in women with dense breast tissue, low suspicion lesions on mammograms, pre-menstrual women with lumps in their breasts and women with locally advanced breast cancer," he added.
Barbara Kerr | EurekAlert!
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Spread of deadly eye cancer halted in cells and animals
13.11.2018 | Johns Hopkins Medicine
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
15.11.2018 | Earth Sciences
15.11.2018 | Physics and Astronomy
15.11.2018 | Physics and Astronomy