Uffe Møller Døhn from the Copenhagen University Hospital at Hvidovre in Denmark and co-workers carried out CT, MRI and radiography on the wrist joints of 17 RA patients and four healthy controls.
Taking CT as the reference method for detecting bone erosions, radiography and MRI both showed good specificity (99% and 93%, respectively) but radiography showed low sensitivity (24%) compared to the moderate sensitivity (61%) of MRI.
They also found that there was strong agreement between the CT and MRI measurements of erosion volumes. The measured volumes also correlated closely with the Outcome Measures in Rheumatology (OMERACT) erosion scores, thus validating this scoring method further.
The researchers said the results show that CT may be useful for detecting and monitoring bone erosion in RA. Dr Møller Døhn stated: “The number of erosions detected on CT indicate that CT is a very sensitive method for detecting bone erosions in RA wrist bones, possibly even more sensitive than MRI.”
However, he acknowledged that the technique’s sensitivity to change was not yet established and that its use of ionizing radiation and inability to detect soft tissue changes did count against it.
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences