Led by Director Dr Metodi Metodiev, the unit has uncovered a panel of protein biomarkers which could lead to improved diagnosis of tumour types and fine-tuned treatment.
‘When we set up the Proteomics Unit here we immediately turned our attention to human issues and the treatment of disease,’ said Dr Metodiev.
Each year more than 42,000 people in the UK are diagnosed with breast cancer, 99 per cent of whom are women. Research has highlighted several risk factors associated with the disease, but better markers are needed for diagnosis, prognosis and therapy. The new technology of proteomics, which is the large-scale study of proteins which are vital components of living organisms as well as tumours, promises to deliver breakthroughs into cancer biomarkers.
‘With proteomics, analysis that took a month to perform can now be done in a second. This gives us a lot more information and is bringing about a very significant change to the way we approach cancer,’ said Dr Metodiev.
Working with Dr Louise Alldridge from Anglia Ruskin University, Chelmsford, clinicians from Broomfield Hospital, Chelmsford, and the Breast Unit at Chelmsford and Essex Hospital, the scientists have examined thousands of proteins in tumour and normal human tissue. They have determined a panel of prospective biomarkers and are now narrowing it down to see what patterns emerge, before a large scale clinical trial can be attempted.
Kate Clayton | alfa
Collagen nanofibrils in mammalian tissues get stronger with exercise
14.12.2018 | University of Illinois College of Engineering
New discoveries predict ability to forecast dementia from single molecule
12.12.2018 | UT Southwestern Medical Center
Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.
Around the world, researchers are attempting to shrink data storage devices to achieve as large a storage capacity in as small a space as possible. In almost...
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
18.12.2018 | Materials Sciences
18.12.2018 | Physics and Astronomy
18.12.2018 | Physics and Astronomy