Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Relief of urinary symptoms is an underappreciated benefit of early stage prostate cancer treatment

21.05.2012
BIDMC findings presented at American Urological Association Annual Meeting

Treatment of early stage prostate cancer can also result in improved quality of life for a subgroup of men who suffer from lower urinary tract symptoms (LUTS), according to an abstract of a Beth Israel Deaconess Medical Center-led study presented to the American Urological Association.

LUTS, which includes problems of frequent or urgent urination, particularly at night, is a common problem that affects approximately 40 percent of men, a percentage that rises with age. It is not a reason to suspect prostate cancer.

"Possible benefits of prostate cancer treatment in alleviating lower urinary tract symptoms have been largely overlooked," says Martin G. Sanda, MD, Director of the Prostate Center at Beth Israel Deaconess Medical Center and Professor of Urology at Harvard Medical School. "We sought to identify pretreatment determinants of urinary function benefit versus worsening due to prostate cancer treatment."

Researchers prospectively evaluated 1,812 men who underwent prostate removal surgery, radiation therapy and brachytherapy or the implant of radioactive "seeds" across the United States and in Spain. They found use of urinary medications was reduced two years after radical prostatectomy surgery compared to pretreatment, while it was unchanged after radiation and became worse after brachytherapy.

Overall bother from urinary treatment (reflecting combined effects of obstruction or incontinence) was unchanged from pretreatment in 86 percent of the men, improved in 7 percent of the cases and worsened in 7 percent.

"The burden of obstructive lower urinary tract symptoms, which is present in one-third of early stage prostate cancer patients, is underappreciated and deserving of greater emphasis in prostate cancer care decisions," says Sanda. "Contrary to conventional assumptions, the number of men whose health-related quality of life is benefited by early stage prostate cancer treatment is similar to the number who quality of life is adversely impacted. Men with lower urinary tract symptoms may be particularly likely to have a better quality of life benefit from radical prostatectomy."

Coauthors of the study included investigators from the PROSTQA Consortium, funded by the National Cancer Institute, and a team of collaborators from Spain.

Beth Israel Deaconess Medical Center is a patient care, teaching and research affiliate of Harvard Medical School, and currently ranks third in National Institutes of Health funding among independent hospitals nationwide. BIDMC is clinically affiliated with the Joslin Diabetes Center and is a research partner of Dana-Farber/Harvard Cancer Center. BIDMC is the official hospital of the Boston Red Sox.

Jerry Berger | EurekAlert!
Further information:
http://www.bidmc.org

More articles from Health and Medicine:

nachricht Researchers find trigger that turns strep infections into flesh-eating disease
19.02.2019 | Houston Methodist

nachricht Loss of identity in immune cells explained
18.02.2019 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light from a roll – hybrid OLED creates innovative and functional luminous surfaces

Up to now, OLEDs have been used exclusively as a novel lighting technology for use in luminaires and lamps. However, flexible organic technology can offer much more: as an active lighting surface, it can be combined with a wide variety of materials, not just to modify but to revolutionize the functionality and design of countless existing products. To exemplify this, the Fraunhofer FEP together with the company EMDE development of light GmbH will be presenting hybrid flexible OLEDs integrated into textile designs within the EU-funded project PI-SCALE for the first time at LOPEC (March 19-21, 2019 in Munich, Germany) as examples of some of the many possible applications.

The Fraunhofer FEP, a provider of research and development services in the field of organic electronics, has long been involved in the development of...

Im Focus: Regensburg physicists watch electron transfer in a single molecule

For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.

The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...

Im Focus: University of Konstanz gains new insights into the recent development of the human immune system

Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens

Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...

Im Focus: Transformation through Light

Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light

When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...

Im Focus: Famous “sandpile model” shown to move like a traveling sand dune

Researchers at IST Austria find new property of important physical model. Results published in PNAS

The so-called Abelian sandpile model has been studied by scientists for more than 30 years to better understand a physical phenomenon called self-organized...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Global Legal Hackathon at HAW Hamburg

11.02.2019 | Event News

The world of quantum chemistry meets in Heidelberg

30.01.2019 | Event News

Our digital society in 2040

16.01.2019 | Event News

 
Latest News

A landscape of mammalian development

21.02.2019 | Life Sciences

Surprising findings on forest fires

21.02.2019 | Earth Sciences

Atopic dermatitis: elevated salt concentrations in affected skin

21.02.2019 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>