Blood poisoning, or sepsis, affects about 0.2 percent of the population. It is a serious condition that can lead to septic shock, one of the most common causes of death at Swedish intensive care units. There is therefore a great need for early identification of potentially critical cases among patients.
SuPAR a good marker
The protein suPAR can be used as a marker of blood poisoning. This is shown in a dissertation written by Anna Gustafsson, a doctoral candidate at Malmö University. Gustafsson also found that the protein correlates with the so-called SOFA score, a measure of organ failure that is used in cases of blood poisoning. The protein could thus be used to identify patients who risk developing serious disease.
“Today a number of analyses are put together to identify these patients. It would be much easier and quicker to use suPAR, because only one sample is needed,” she says.Opens new avenues
“We know that saliva reflects the composition of blood. The fact that suPAR in the blood can indicate cancer, diabetes, and other serious diseases means that our findings could open entirely new avenues for tracking various diseases in saliva,” says Gustafsson.
Using saliva instead of blood samples is of great value in screening studies, as samples can be acquired with little bother to patients, who in fact can take the sample themselves at home.Treatment with peptides
“The results show that AMPs moderate the immune defense’s reaction to LPS but strengthen the reaction to LTA. This is a truly unexpected finding, which hypothetically could mean that peptide treatment of LTA might aggravate the condition,” says Gustafsson.
For further information please contact Anna Gustafsson; Telephone: +46 40-66 57416 or mobile phone: +46 70 – 53 46 645 or E-mail: email@example.com
Charlotte Löndahl Bechmann | idw
Spread of deadly eye cancer halted in cells and animals
13.11.2018 | Johns Hopkins Medicine
Breakthrough in understanding how deadly pneumococcus avoids immune defenses
13.11.2018 | University of Liverpool
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
13.11.2018 | Life Sciences
13.11.2018 | Life Sciences
13.11.2018 | Awards Funding