Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

PolyU study sheds new light on anti-inflammatory mechanism of unique marine oil

26.01.2009
A pioneering research by The Hong Kong Polytechnic University (PolyU) has uncovered the previously unknown anti-inflammatory mechanism for soothing the pain arising from arthritis, and thus unlocked the key to conducting further researches on the relationship between functional foods and this common crippling disease.

This research was undertaken by a team led by Professor Samuel Lo Chun-lap of the Department of Applied Biology and Chemical Technology in the University’s Proteomics Laboratory. The team was intrigued by whether consumption of a food supplement would alleviate the symptom of arthritis, and they started with testing the oil of Perna canaliculus, the green-lipped mussel of New Zealand, on rats with adjuvant-induced arthritis.

In a series of studies conducted by Professor Lo and his team, the oil extract was shown to be able to relieve pain in the animals; modulate cytokines with a decrease in cytokines associated with inflammation, and lead to an increase in IL-10 (a cytokine that controls inflammation).

More importantly, the oil extract decreased the synthesis of some proteins associated with inflammation, while increasing the synthesis of the anti-inflammatory enzyme MDH. Decreased expression of proteins related to inflammation was uncovered by proteomic technologies. This discovery has therefore cast new light on the anti-inflammatory function of this oil and the underlying mechanism of soothing arthritis.

The result of this ground-breaking study was published under the title of “Differential protein expression induced by a lipid extract of Perna canaliculus in splenocytes of rats with adjuvant-induced arthritis” in the Inflammopharmacology journal in 2008.

Encouraged by the findings, PolyU researchers are planning to test the anti-inflammatory functions of other common foods as well as Chinese herbs. They will also involve athletes and sportsmen besieged by arthritis in the next stage of research. Prof. Lo will be working alongside with Associate Professor Dr Mason Leung of the University’s Department of Rehabilitation Sciences in the next stage.

The oil of Perna canaliculus, the green-lipped mussel of New Zealand, when extracted by super-critical extraction is free of protein and carbohydrate. A large number of studies have been published on its composition, complex mode of action, activity in animal models, and efficacy in controlling osteoarthritis and moderate asthma in patients.

These studies were supported in part by an unrestricted grant for education and research from Pharmalink International Ltd.

Press Contact: Professor Samuel Lo
Department of Applied Biology and Chemical Technology
Telephone: (852) 3400 8669
E-mail: bcsamlo@polyu.edu.hk

Yu Kit Sun Regina | ResearchSEA
Further information:
http://www.polyu.edu.hk
http://www.researchsea.com

More articles from Health and Medicine:

nachricht Potential seen for tailoring treatment for acute myeloid leukemia
10.12.2018 | University of Washington Health Sciences/UW Medicine

nachricht UC San Diego researchers develop sensors to detect and measure cancer's ability to spread
06.12.2018 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers develop method to transfer entire 2D circuits to any smooth surface

What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.

Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...

Im Focus: Three components on one chip

Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.

Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...

Im Focus: Substitute for rare earth metal oxides

New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals

Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.

Im Focus: A bit of a stretch... material that thickens as it's pulled

Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.

Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...

Im Focus: The force of the vacuum

Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.

The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

New Plastics Economy Investor Forum - Meeting Point for Innovations

10.12.2018 | Event News

EGU 2019 meeting: Media registration now open

06.12.2018 | Event News

Expert Panel on the Future of HPC in Engineering

03.12.2018 | Event News

 
Latest News

New method gives microscope a boost in resolution

10.12.2018 | Physics and Astronomy

Carnegie Mellon researchers probe hydrogen bonds using new technique

10.12.2018 | Life Sciences

ETRI exchanged quantum information on daylight in a free-space quantum key distribution

10.12.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>