People in there 80s and 90s are more likely to develop acute coronary syndrome than their younger counterparts. Despite this, they receive less therapy and diagnostic procedures. A doctoral thesis at Sahlgrenska Academy has explored the topic.
Previous studies have shown that older patients are less likely to receive the most evidence-based, recommended treatment for acute coronary syndrome. Regarding the elderly, quality and quantity of the underlying scientific evidence is limited.
Berglind Libungan, PhD Student, University of Gothenburg
University of Gothenburg
A number of recent studies by researchers at Sahlgrenska Academy have included more than 45,000 elderly cardiac patients. Presented in Dr. Berglind Libungan's doctoral thesis, the studies found that treatment of patients with symptoms of acute coronary syndrome, to some extent, is age-related.
• Although patients with chest pain in their 80s and 90s are more likely to have a final diagnosis of acute coronary syndrome, they do less angiograms, echocardiograms and receive less medical therapy compared with their younger counterparts. However, there was not a delay to hospitalization or therapy when compared to younger patients.
"I presume that older patients receive less evidence-based treatment because the treating physician feels that the risks outweigh the benefits," Dr. Libungan says.
• The risk for death, among older patients with myocardial infarction who are treated with medical therapy, is higher than among patients who do an intervention, coronary angioplasty.
"Given the major differences between various patient groups, this finding does not mean that interventions are automatically better," Dr. Libungan says. “Patients who are treated with medication alone are usually older and in poorer health. Additional clinical research is needed to determine the strategy that works best for older patients.”
• The number of elderly Swedes with myocardial infarction treated with balloon angioplasty has increased over the past decade. Even though they are generally older and sicker, the risk for complications has not increased.
"The evidence suggests that more elderly patients could be offered balloon angioplasty," Dr. Libungan says.
Higher mortality rate
The new studies have also found that elderly patients who suffer cardiac arrest have a higher mortality rate which increases with age. The survival rate is 6.6% among 70-80 year-olds, 4.4% among 80-90 year-olds and 2.3% among those older than 90.
Mr. Libungan will defend his thesis, "Acute coronary syndrome and cardiac arrest in the elderly" on May 28.
Link to thesis: http://hdl.handle.net/2077/38347
Berglind Libungan, PhD Student, Sahlgrenska Academy, University of Gothenburg
Supervisor: Per Albertsson
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