"During seizures, a patient's heart rate most often increases significantly, but in about 1 percent of this population, a seizure will lead to the heart stopping for a brief period of time," says Jeffrey W. Britton, M.D., a Mayo Clinic neurologist and member of the research team.
"The heart almost always restarts on its own, but sometimes as much as 20 to 30 seconds can pass where no blood flows to the brain and causes the patient to collapse and fall during a seizure."
The brief period when the heart stops can lead to significant injury. "In this study, we wanted to determine if, in addition to medication, there would be any benefit to reducing falls by implanting a pacemaker," says researcher Brian D. Moseley, M.D., a Mayo Clinic resident and neurology instructor.
Researchers identified seven patients who were diagnosed with ictal asystole and had a history of falls associated with it before undergoing cardiac pacing at Mayo Clinic between 1990 and 2004.
Patients with the condition were identified through observation of their seizures during computer-assisted continuous video electroencephalography/electrocardiography (EEG/ECG).
Researchers found the rate of injury and falls declined after the patients received their implants. "Before implantation, the average fall rate was more than three falls per month; following implantation, this was reduced to 0.005 falls per month," Dr. Britton says.
In addition, three of the seven patients needed less seizure medication after receiving their implants. "This may argue that in addition to helping reduce falls there may be some anti-seizure properties associated with pacemaker implantation. That's an exciting finding that needs to be studied some more," says Dr. Moseley.
Other members of the Mayo Clinic research team include Gena Ghearing, M.D., now of the University of Pittsburgh Medical Center, and Thomas Munger, M.D. The study was published online February 14, 2011.About Mayo Clinic
Brian Kilen | EurekAlert!
Unique brain 'fingerprint' can predict drug effectiveness
11.07.2018 | McGill University
Direct conversion of non-neuronal cells into nerve cells
03.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
18.07.2018 | Life Sciences
18.07.2018 | Life Sciences
18.07.2018 | Information Technology