Men who at the age of 18 years have poorer cardiovascular fitness and/or a lower IQ more often suffer from dementia before the age of 60. This is shown in a recent study encompassing more than one million Swedish men.
In several extensive studies, researchers at the Sahlgrenska Academy of The University of Gothenburg have previously analyzed Swedish men's conscription results and were able to show a correlation between cardiovascular fitness as a teenager and health problems in later life.
Jenny Nyberg, Ph.D. and Researcher at Sahlgrenska Academy, Gothenburg University
The University of Gothenburg
Increased risk for early-onset dementia
In their latest study, based on data from 1.1 million young Swedish men, the Gothenburg researcher team shows that those with poorer cardiovascular fitness and/or lower IQ in their teenage years more often suffer from early-onset dementia.
"Previous studies have shown the correlation between cardiovascular fitness and the risk of dementia in old age. Now, for the first time, we can show that the increased risk also applies to early-onset dementia and its precursors," says Sahlgrenska Academy researcher Jenny Nyberg, who headed the study.
Controlled for other risk factors
Expressed in figures, the study shows that men who when conscripted had poorer cardiovascular fitness were 2.5 times more likely to develop early-onset dementia later in life. A lower IQ entailed a 4 times greater risk, and a combination of both poor cardiovascular fitness and low IQ entailed a 7 times greater risk of early-onset dementia.
The increased risk remained even when controlled for other risk factors, such as heredity, medical history, and social-economic circumstances.
Fitness strengthens the brain
"We already knew that physical and cognitive exercise reduces the risk of neurological disease. Physical exercise increases nerve cell complexity and function and even generation of new nerve cells in the adult brain, which strengthens our mental and physiological functions. In other words, good cardiovascular fitness makes the brain more resistant to damage and disease," says Prof. Georg Kuhn, senior author of the study.
People who develop early-onset dementia are often of working age and can have children still living at home, which means the consequences for both the sufferers and their families are even more serious. Despite this, patients with early-onset dementia are a relatively overlooked group.
"This makes it important to initiate more research into how physical and mental exercise can affect the prevalence of different types of dementia. Perhaps exercise can be used as both a prophylactic and a treatment for those in the risk zone for early-onset dementia," says Nyberg.
The article Cardiovascular and cognitive fitness at age 18 and risk of early-onset dementia was published online in the scientific journal Brain on 7 March.
Link to article: http://brain.oxfordjournals.org/content/early/2014/03/06/brain.awu041.abstract
FACTS ABOUT DEMENTIA AND THE QUOTED STUDY
Dementia is not a disease but a group of different diseases characterized by the gradual worsening of cognitive abilities. Dementia is seen across all ethnic groups and increasingly so with advancing age. Among 65–69-year-olds, about 2 percent are afflicted, with this figure doubling for every five years of age.
The quoted study encompassed all Swedish men conscripted for mandatory military service between the years 1968 and 2005, a total of 1.1 million individuals. In the study, the researchers have compared the results from the conscripts' cardiovascular fitness and IQ tests with information from national disease registries. During the study period, a total of 660 men were diagnosed with early-onset dementia.
Jenny Nyberg, Ph.D. and Researcher at Sahlgrenska Academy, The University of Gothenburg, firstname.lastname@example.org
Georg Kuhn, Professor and Researcher at Sahlgrenska Academy, The University of Gothenburg, email@example.com
Krister Svahn | idw - Informationsdienst Wissenschaft
UC San Diego researchers develop sensors to detect and measure cancer's ability to spread
06.12.2018 | University of California - San Diego
New cancer immunotherapy approach turns immune cells into tiny anti-tumor drug factories
05.12.2018 | University of California - San Diego
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals
Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.
Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.
Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...
Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.
The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.
06.12.2018 | Event News
03.12.2018 | Event News
28.11.2018 | Event News
07.12.2018 | Life Sciences
07.12.2018 | Materials Sciences
07.12.2018 | Physics and Astronomy