A research team led by investigators at Mayo Clinic in Florida has found that a small device worn on a patient's brow can be useful in monitoring stroke patients in the hospital. The device measures blood oxygen, similar to a pulse oximeter, which is clipped onto a finger.
Their study, published in the Feb. 1 issue of Neurosurgical Focus, suggests this tool, known as frontal near-infrared spectroscopy (NIRS), could offer hospital physicians a safe and cost-effective way to monitor patients who are being treated for a stroke, in real time.
"About one-third of stroke patients in the hospital suffer another stroke, and we have few options for constantly monitoring patients for such recurrences," says the study's senior investigator, neurocritical care specialist William Freeman, M.D., an associate professor of neurology at Mayo Clinic.
"This was a small pilot study initiated at Mayo Clinic's campus in Florida, but we plan to study this device more extensively and hope that this bedside tool offers significant benefit to patients by helping physicians detect strokes earlier and manage recovery better," he says.
Currently, at most hospitals nurses monitor patients for new strokes and, if one is suspected, patients must be moved to a hospital's radiology unit for a test known as a CT perfusion scan, which is the standard way to measure blood flow and oxygenation. This scan requires that a contrast medium be used, and the entire procedure can sometimes cause side effects such as excess radiation exposure if repeated scans are required. Also, potential kidney and airway damage can result from the contrast medium.
Alternately, for the sickest patients, physicians can insert an oxygen probe inside the brain to measure blood and oxygen flow, but this procedure is invasive and measures only a limited brain region, Dr. Freeman says.
This NIRS device, which emits near-infrared light that penetrates the scalp and underlying brain tissue, has been used in animals to study brain blood, so the Mayo Clinic team thought that measuring the same parameters in stroke patients might be useful. They set up a study to compare measurements from NIRS with CT perfusion scanning in eight stroke patients.
The results show that both tests offer statistically similar results, although NIRS has a more limited field for measuring blood oxygen and flow. "That suggests that perhaps not all patients would benefit from this kind of monitoring," he says.
The device sticks like an adhesive bandage onto each of the patient's eyebrows and works like the pulse oximeter that is usually used on a patient's finger to monitor health or brain perfusion during surgery.
If the device is successfully tested in upcoming studies and miniaturized, the NIRS might also be useful in military settings to assess and monitor blood functioning due to brain injuries, Dr. Freeman says.
Researchers from the University of South Florida College of Medicine and the University of North Florida College of Medicine participated in the study, along with several college students who were participating in Mayo Clinic's Clinical Research Scholar Program (CRISP).
"This research could not have been accomplished without the dedication and assistance from our CRISP premedical student Brandon O'Neal, and vascular neurosurgery fellow Philipp Taussky, M.D.," notes Dr. Freeman. "We are excited about the future possibilities in which this tool would be very useful."
The study was approved by the Mayo Clinic IRB and not sponsored or funded by any company. The authors declare no conflicts of interest.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit MayoClinic.com or MayoClinic.org/news.
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Spread of deadly eye cancer halted in cells and animals
13.11.2018 | Johns Hopkins Medicine
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
14.11.2018 | Materials Sciences
14.11.2018 | Health and Medicine
14.11.2018 | Life Sciences