A research team led by investigators at Mayo Clinic in Florida has found that a small device worn on a patient's brow can be useful in monitoring stroke patients in the hospital. The device measures blood oxygen, similar to a pulse oximeter, which is clipped onto a finger.
Their study, published in the Feb. 1 issue of Neurosurgical Focus, suggests this tool, known as frontal near-infrared spectroscopy (NIRS), could offer hospital physicians a safe and cost-effective way to monitor patients who are being treated for a stroke, in real time.
"About one-third of stroke patients in the hospital suffer another stroke, and we have few options for constantly monitoring patients for such recurrences," says the study's senior investigator, neurocritical care specialist William Freeman, M.D., an associate professor of neurology at Mayo Clinic.
"This was a small pilot study initiated at Mayo Clinic's campus in Florida, but we plan to study this device more extensively and hope that this bedside tool offers significant benefit to patients by helping physicians detect strokes earlier and manage recovery better," he says.
Currently, at most hospitals nurses monitor patients for new strokes and, if one is suspected, patients must be moved to a hospital's radiology unit for a test known as a CT perfusion scan, which is the standard way to measure blood flow and oxygenation. This scan requires that a contrast medium be used, and the entire procedure can sometimes cause side effects such as excess radiation exposure if repeated scans are required. Also, potential kidney and airway damage can result from the contrast medium.
Alternately, for the sickest patients, physicians can insert an oxygen probe inside the brain to measure blood and oxygen flow, but this procedure is invasive and measures only a limited brain region, Dr. Freeman says.
This NIRS device, which emits near-infrared light that penetrates the scalp and underlying brain tissue, has been used in animals to study brain blood, so the Mayo Clinic team thought that measuring the same parameters in stroke patients might be useful. They set up a study to compare measurements from NIRS with CT perfusion scanning in eight stroke patients.
The results show that both tests offer statistically similar results, although NIRS has a more limited field for measuring blood oxygen and flow. "That suggests that perhaps not all patients would benefit from this kind of monitoring," he says.
The device sticks like an adhesive bandage onto each of the patient's eyebrows and works like the pulse oximeter that is usually used on a patient's finger to monitor health or brain perfusion during surgery.
If the device is successfully tested in upcoming studies and miniaturized, the NIRS might also be useful in military settings to assess and monitor blood functioning due to brain injuries, Dr. Freeman says.
Researchers from the University of South Florida College of Medicine and the University of North Florida College of Medicine participated in the study, along with several college students who were participating in Mayo Clinic's Clinical Research Scholar Program (CRISP).
"This research could not have been accomplished without the dedication and assistance from our CRISP premedical student Brandon O'Neal, and vascular neurosurgery fellow Philipp Taussky, M.D.," notes Dr. Freeman. "We are excited about the future possibilities in which this tool would be very useful."
The study was approved by the Mayo Clinic IRB and not sponsored or funded by any company. The authors declare no conflicts of interest.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit MayoClinic.com or MayoClinic.org/news.
New 3D cultured cells mimic the progress of NASH
02.04.2020 | Tokyo University of Agriculture and Technology
Geneticists are bringing personal medicine closer to recently admixed individuals
02.04.2020 | Estonian Research Council
Drops of water falling on or sliding over surfaces may leave behind traces of electrical charge, causing the drops to charge themselves. Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz have now begun a detailed investigation into this phenomenon that accompanies us in every-day life. They developed a method to quantify the charge generation and additionally created a theoretical model to aid understanding. According to the scientists, the observed effect could be a source of generated power and an important building block for understanding frictional electricity.
Water drops sliding over non-conducting surfaces can be found everywhere in our lives: From the dripping of a coffee machine, to a rinse in the shower, to an...
90 million-year-old forest soil provides unexpected evidence for exceptionally warm climate near the South Pole in the Cretaceous
An international team of researchers led by geoscientists from the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) have now...
The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply. When the iron transport into the bacteria is inhibited, the pathogen can no longer grow. This opens novel ways to develop targeted tuberculosis drugs.
One of the most devastating pathogens that lives inside human cells is Mycobacterium tuberculosis, the bacillus that causes tuberculosis. According to the...
An international team with the participation of Prof. Dr. Michael Kues from the Cluster of Excellence PhoenixD at Leibniz University Hannover has developed a new method for generating quantum-entangled photons in a spectral range of light that was previously inaccessible. The discovery can make the encryption of satellite-based communications much more secure in the future.
A 15-member research team from the UK, Germany and Japan has developed a new method for generating and detecting quantum-entangled photons at a wavelength of...
Together with their colleagues from the University of Würzburg, physicists from the group of Professor Alexander Szameit at the University of Rostock have devised a “funnel” for photons. Their discovery was recently published in the renowned journal Science and holds great promise for novel ultra-sensitive detectors as well as innovative applications in telecommunications and information processing.
The quantum-optical properties of light and its interaction with matter has fascinated the Rostock professor Alexander Szameit since College.
02.04.2020 | Event News
26.03.2020 | Event News
23.03.2020 | Event News
03.04.2020 | Materials Sciences
03.04.2020 | Life Sciences
03.04.2020 | Life Sciences