Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New groundbreaking treatment for oxygen-deprived newborns

11.08.2009
Until now immediate cooling of the newborn infant was the only treatment that could possibly prevent brain damage following oxygen deprivation during delivery.

New research findings from the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital, Sweden, in collaboration with Zhengzhou University in China, open up the possibility of a new and effective treatment that can be started as late as two days after birth.

This new treatment involves newborn infants being given a two-week course of injections of erythropoietin, a hormone that stimulates the formation of red blood cells.

"For the first time we can demonstrate that it is possible to influence the brain damage occurring as a result of oxygen deprivation during delivery considerably later than the six-hour window of opportunity for treating with cooling," says Klas Blomgren, professor of paediatrics at the Sahlgrenska Academy and specialist at Queen Silvia Children's Hospital.

The research findings, which are presented in the latest issue of the highly-respected medical journal Pediatrics, are the result of cooperation between Swedish, Austrian and Chinese researchers. The study treated just over 150 term newborn infants, half of whom were given small doses of erythropoietin every other day. Once the children reached the age of eighteen months, their neurological condition was assessed.

"Only half as many of the children treated with erythropoietin had developed a severe neurological functional disability or had died of their injuries. Thus the hormone treatment improves the prognosis considerably in the longer perspective," says Blomgren.

The children in the study had suffered moderate or severe hypoxic-ischemic encephalopathy (HIE) at birth, but it was only children with moderate HIE that were helped by this hormone treatment.

"We believe that erythropoietin has a regenerative and stimulating effect on recovery and on brain development following the injury. This appears to be a safe treatment, almost without side effects, and it is also cheaper and technically simpler to administer in comparison with cooling. This means that the treatment can be given a wide distribution, and can be used even in developing countries," says Blomgren.

For further information, contact:
Klas Blomgren, professor of paediatrics at the Sahlgrenska Academy and specialist at Queen Silvia's Children's Hospital, telephone +46 (0)31-786 33 76, +46 (0)31-343 59 06 or +46 (0)70-323 33 53, klas.blomgren@neuro.gu.se

Helena Aaberg | idw
Further information:
http://www.gu.se
http://www.sahlgrenska.gu.se

More articles from Health and Medicine:

nachricht Photoactive bacteria bait may help in fight against MRSA infections
12.10.2018 | Purdue University

nachricht 15 emerging technologies that could reduce global catastrophic biological risks
10.10.2018 | Johns Hopkins Center for Health Security

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Storage & Transport of highly volatile Gases made safer & cheaper by the use of “Kinetic Trapping"

Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles

Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...

Im Focus: Disrupting crystalline order to restore superfluidity

When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.

We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...

Im Focus: Micro energy harvesters for the Internet of Things

Fraunhofer IWS Dresden scientists print electronic layers with polymer ink

Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...

Im Focus: Dynamik einzelner Proteine

Neue Messmethode erlaubt es Forschenden, die Bewegung von Molekülen lange und genau zu verfolgen

Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...

Im Focus: Dynamics of individual proteins

New measurement method allows researchers to precisely follow the movement of individual molecules over long periods of time

The function of proteins – the molecular tools of the cell – is governed by the interplay of their structure and dynamics. Advances in electron microscopy have...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Berlin5GWeek: Private industrial networks and temporary 5G connectivity islands

16.10.2018 | Event News

5th International Conference on Cellular Materials (CellMAT), Scientific Programme online

02.10.2018 | Event News

Major Project: The New Silk Road

01.10.2018 | Event News

 
Latest News

Unravelling the genetics of fungal fratricide

16.10.2018 | Life Sciences

Blue phosphorus -- mapped and measured for the first time

16.10.2018 | Physics and Astronomy

Berlin5GWeek: Private industrial networks and temporary 5G connectivity islands

16.10.2018 | Event News

VideoLinks
Science & Research
Overview of more VideoLinks >>>