Influenza is a major cause of serious respiratory disease in pregnant women and of hospitalization in infants. Although the flu vaccine is recommended for all pregnant women and children, no vaccine is approved for infants under six months of age. Preventive strategies for this age group include general infection control and vaccination of those coming in close contact with them.
First author Isaac Benowitz, a Yale medical student, senior author Marietta Vazquez, M.D., and their colleagues examined the effectiveness of flu vaccine during pregnancy in preventing hospitalization in infants. The study enrolled infants hospitalized at Yale-New Haven Hospital due to influenza and a similar group of infants without influenza. The researchers then compared whether each infant's mother had gotten the flu vaccine during pregnancy.
"When we compared vaccination rates during pregnancy in the study, we found that in the group of infants who didn't have influenza, far more mothers received the influenza vaccine," said Vazquez, assistant professor in the Department of Pediatrics at Yale. "In the group of infants studied, giving the vaccine to a woman during pregnancy was 91.5 percent effective in preventing hospitalization due to influenza."
Vazquez said that the study's findings provide an effective strategy for protecting infants under six months old, for whom no vaccine is available. She also points out that vaccination during pregnancy is cost-effective, as one vaccine protects two individuals.
Other Yale authors on the study include Daina B. Esposito, Kristina D. Gracey and Eugene D. Shapiro, M.D.
Citation: Clinical Infectious Diseases 2010, 51 (12) (December 15, 2010)
Karen Peart | EurekAlert!
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
08.08.2018 | Event News
27.07.2018 | Event News
25.07.2018 | Event News
17.08.2018 | Materials Sciences
17.08.2018 | Information Technology
17.08.2018 | Physics and Astronomy