Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early nutrition has a long-term metabolic impact

02.05.2011
Growth, hormonal profiles differ between breastfed, formula-fed infants

Nutrition during the first days or weeks of life may have long-term consequences on health, potentially via a phenomenon known as the metabolic programming effect, according to a study to be presented Monday, May 2, at the Pediatric Academic Societies (PAS) annual meeting in Denver.

Metabolic programming is the concept that differences in nutritional experiences at critical periods early in life can program a person's metabolism and health for the future.

In this study, researchers compared growth, body composition and blood pressure in three groups of healthy, full-term newborns in the Neonatal Department of Hospices Civils de Lyon, Claude Bernard University, Lyon, France. One group received only breast milk for the first four months of life. The two other groups were randomized to receive either a low-protein formula with 1.8 grams of protein/100 kilocalories (g/kcal) or a high-protein formula with 2.7 g/100 kcal. The protein content of both formulas was within the recommended levels of 1.8 to 3 g/100 kcal.

After four months, the formula-fed infants continued to receive the same formula, and the breastfed infants were assigned to the low-protein formula, if needed.

Researchers, who followed 234 children for three years, found that exclusive breastfeeding during the first weeks of life induced a specific pattern of growth and a specific metabolic profile, which appeared to differ in formula-fed infants. The protein content in infant formula may be a key factor in inducing these differences, according to study co-author Guy Putet, MD.

As early as 15 days of life, blood insulin levels were lower in breastfed infants than in formula-fed infants. These differences persisted at 4 months of age, but no differences were seen at 9 months.

Growth patterns also were different between groups during the first year of life, but by 3 years of age, there no longer was any difference in length, weight or body composition (fat mass, lean body mass) between groups. The exception was head circumference, which was slightly lower in the low-protein formula group but still well within the normal range.

At 3 years, an unexpected result was that diastolic and mean blood pressures were higher in the infants who had been fed the high-protein formula compared to the breastfed infants, Dr. Putet noted. However, these levels were still within the normal range.

"It appears that formula feeding induces differences in some hormonal profiles as well as in patterns of growth compared with breastfeeding," Dr. Putet said. "The long-term consequences of such changes are not well-understood in humans and may play a role in later health. Well-designed studies with long-term follow-up are needed."

If breastfeeding is not possible, Dr. Putet concluded, infants should be fed formulas that allow a growth pattern and a metabolic profile similar to that of breastfed infants.

To view the abstract, go to http://www.abstracts2view.com/pas/view.php?nu=PAS11L1_925.

The Pediatric Academic Societies (PAS) are four individual pediatric organizations who co-sponsor the PAS Annual Meeting – the American Pediatric Society, the Society for Pediatric Research, the Academic Pediatric Association, and the American Academy of Pediatrics. Members of these organizations are pediatricians and other health care providers who are practicing in the research, academic and clinical arenas. The four sponsoring organizations are leaders in the advancement of pediatric research and child advocacy within pediatrics, and all share a common mission of fostering the health and well being of children worldwide. For more information, visit www.pas-meeting.org. Follow news of the PAS meeting on Twitter at http://twitter.com/PedAcadSoc.

Susan Martin | EurekAlert!
Further information:
http://www.aap.org

Further reports about: PAS Pediatric academic blood pressure body composition formula-fed infants societies

More articles from Health and Medicine:

nachricht New way to target advanced breast cancers
24.09.2018 | Jackson Laboratory

nachricht Neutrons produce first direct 3D maps of water during cell membrane fusion
21.09.2018 | DOE/Oak Ridge National Laboratory

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Hygiene at your fingertips with the new CleanHand Network

The Fraunhofer FEP has been involved in developing processes and equipment for cleaning, sterilization, and surface modification for decades. The CleanHand Network for development of systems and technologies to clean surfaces, materials, and objects was established in May 2018 to bundle the expertise of many partnering organizations. As a partner in the CleanHand Network, Fraunhofer FEP will present the Network and current research topics of the Institute in the field of hygiene and cleaning at the parts2clean trade fair, October 23-25, 2018 in Stuttgart, at the booth of the Fraunhofer Cleaning Technology Alliance (Hall 5, Booth C31).

Test reports and studies on the cleanliness of European motorway rest areas, hotel beds, and outdoor pools increasingly appear in the press, especially during...

Im Focus: Scientists present new observations to understand the phase transition in quantum chromodynamics

The building blocks of matter in our universe were formed in the first 10 microseconds of its existence, according to the currently accepted scientific picture. After the Big Bang about 13.7 billion years ago, matter consisted mainly of quarks and gluons, two types of elementary particles whose interactions are governed by quantum chromodynamics (QCD), the theory of strong interaction. In the early universe, these particles moved (nearly) freely in a quark-gluon plasma.

This is a joint press release of University Muenster and Heidelberg as well as the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.

Then, in a phase transition, they combined and formed hadrons, among them the building blocks of atomic nuclei, protons and neutrons. In the current issue of...

Im Focus: Patented nanostructure for solar cells: Rough optics, smooth surface

Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.

"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...

Im Focus: New soft coral species discovered in Panama

A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.

Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...

Im Focus: New devices based on rust could reduce excess heat in computers

Physicists explore long-distance information transmission in antiferromagnetic iron oxide

Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

"Boston calling": TU Berlin and the Weizenbaum Institute organize a conference in USA

21.09.2018 | Event News

One of the world’s most prominent strategic forums for global health held in Berlin in October 2018

03.09.2018 | Event News

4th Intelligent Materials - European Symposium on Intelligent Materials

27.08.2018 | Event News

 
Latest News

Why it doesn’t get dark when you blink

25.09.2018 | Life Sciences

Genome Duplication Drives Evolution of Species

25.09.2018 | Life Sciences

Desert ants have an amazing odor memory

25.09.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>