Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Disease-, Age-Related Effects of HIV May Impact Driving Abilities of Middle-Aged and Older Adults

03.04.2014

Nearly half of people living with HIV experience cognitive deficits that may impact instrumental activities of daily living, including driving, according to University of Alabama at Birmingham School of Nursing research published in the March issue of the Journal of the Association of Nurses in AIDS Care.

“As the number of people aging with HIV increases, concerns mount that disease-related cognitive deficits may be compounded by age-related deficits,” said David E. Vance, Ph.D., associate director of the Center for Nursing Research and principal investigator of the research. “Disease-related deficits may be compounded by age-related deficits, which may further compromise everyday functions such as driving.”


UAB News

UAB School of Nursing researcher David Vance says as the number of people aging with HIV increases, concerns mount that disease-related cognitive deficits may be compounded by age-related deficits.

In a cross-sectional pilot study funded by a pilot grant from the National Institutes of Health-funded UAB Center for AIDS Research, 26 adults age 40 and older were administered demographic, health, psychosocial and driving habit questionnaires, as well as cognitive assessments and driving simulator tests. While the study participants’ viral load — the level of HIV in one’s blood — was unrelated to driving performance, older age was related to poorer driving.

Study results also found that poorer visual speed-of-processing performance, including useful field of view, was related to poorer driving performance, which included average reaction times.

Mixed findings were observed between driving performance and cognitive function on self-reported driving habits of participants.

Previous studies have shown that individuals with HIV, especially as they age, exhibit lower cognitive performance than do uninfected individuals in the domains of speed of processing, psychomotor speed, executive functioning, and learning and memory.

The purpose of this study was to build on this existing research and examine driving simulator performance in an older sample of adults with HIV than in prior studies. The study had three key aims:

Examine relationships between demographic and mental and physical health variables and driving simulator outcomes

Examine relationships between cognitive and everyday functioning measures and driving simulator outcomes

Examine relationships between demographic and mental and physical health variables, and cognitive measures and driving simulator outcomes measures, as well as self-reported driving habits in older adults with HIV

Considering that, by 2015, nearly half of people living with HIV in the United States will be 50 years of age or older, Vance says this is an area that requires further research efforts.

“Driving is perhaps one of the most cognitively complex everyday activities, involving the ability to successfully negotiate one’s environment on the road by making quick decisions and attending and reacting to various stimuli,” Vance said. “The most pronounced and prevalent cognitive deficits in HIV are found in measures of speed and processing — functions essential to safe driving. Previous research shows 29 percent of adults with HIV have indicated a decreased driving ability. That alone means it’s an area that requires further examination.”

The UAB Edward R. Roybal Center for Translational Research in Aging and Mobility provided the infrastructure and facilities for this research. Greer Burkholder, M.D., assistant professor of infectious diseases, supplied information for the research from the UAB School of Medicine’s 1917 Clinic electronic medical database.

About UAB
Known for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, UAB is an internationally renowned research university and academic medical center and the state of Alabama’s largest employer, with some 23,000 employees and an economic impact exceeding $5 billion annually on the state. The five pillars of UAB’s mission deliver knowledge that will change your world: the education of students, who are exposed to multidisciplinary learning and a new world of diversity; research, the creation of new knowledge; patient care, the outcome of ‘bench-to-bedside’ translational knowledge; service to the community at home and around the globe, from free clinics in local neighborhoods to the transformational experience of the arts; and the economic development of Birmingham and Alabama. Learn more at www.uab.edu.

EDITOR’S NOTE: The University of Alabama at Birmingham is a separate, independent institution from the University of Alabama, which is located in Tuscaloosa. Please use University of Alabama at Birmingham on first reference and UAB on all subsequent references.

VIDEO: www.youtube.com/uabnews TEXT: www.uab.edu/news TWEETS: www.twitter.com/uabnews

Tyler Greer | newswise

Further reports about: Abilities Adults Alabama Driving HIV Middle-Aged ability cognitive deficits individuals outcomes relationships

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Nonstop Tranport of Cargo in Nanomachines

20.11.2018 | Life Sciences

Researchers find social cultures in chimpanzees

20.11.2018 | Life Sciences

When AI and optoelectronics meet: Researchers take control of light properties

20.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>