Chronic use of prescription painkillers, also known as opioids, among obese patients prior to bariatric surgery continues after surgery, according to a new Kaiser Permanente study published today in the Journal of the American Medical Association.
Researchers examined the electronic medical records of 11,719 obese patients who underwent bariatric surgery between 2005-2009 at one of 10 U.S. sites in the Scalable Partnering Network. Participating patients were evaluated one year before and one year after surgery. Seventy-seven percent of the obese patients who exhibited chronic opioid use prior to surgery continued to use these medications chronically one year after their procedure. Chronic opioid use among these patients also increased by 13 percent the first year after surgery.
"Obese patients are often more sensitive to pain and tend to be prescribed increasing opioid doses in order to manage that pain," said lead study author Marsha A. Raebel, PharmD, a senior investigator at Kaiser Permanente's Institute for Health Research.
In the year prior to their surgical procedures, 56 percent of the patients in this study reported no opioid use for pain management, 36 percent used some opioids and 8 percent used opioids on a chronic basis. Chronic opioid use was defined as having 10 or more prescriptions over at least 90 days or at least a 120-day total supply of medication sometime in the year prior to surgery. Some opioid use was defined as one to nine prescriptions over 90 days or less than a 120-day supply.
"There are limited options for pain management available to bariatric surgery patients because non-steroidal, anti-inflammatory medications increase the risk of ulcers, particularly after bariatric surgery," said Dr. Raebel. "Given the increasing chronic usage rate reported in this study, it's clear that the medical community needs to develop better pain management programs for patients who use opioids long-term following bariatric surgery."
More than 200,000 bariatric surgeries were performed in the U.S. in 2012 and prescription painkiller usage has exploded at the same time. According to the medical journal Pain, 4.3 million adults use opioid medications on a regular basis. The most commonly used prescription opioids are hydrocodone, oxycodone and morphine. Long-term opioid use can lead to many health issues, the most serious being addiction and fatal overdoses.
Kaiser Permanente is committed to furthering understanding of chronic opioid use. Earlier in 2013, a Kaiser Permanente study found that regularly taking opioids increases a man's risk of erectile dysfunction.
Kaiser Permanente can conduct transformational health research like this in part because it has the largest private patient-centered electronic health record system in the world. The organization's electronic health record system, Kaiser Permanente HealthConnect®, securely connects 9.1 million patients to 17,000 physicians in 611 medical offices and 37 hospitals. It also connects Kaiser Permanente's research scientists to one of the most extensive collections of longitudinal medical data available, facilitating studies and important medical discoveries that shape the future of health care delivery for patients and the medical community.
Additional study authors include: Sophia R. Newcomer, MPH, Liza M. Reifler, MPH, and Elizabeth A. Bayliss, MD, MSPH, of the Kaiser Permanente Institute for Health Research; Denise Boudreau, PhD, of Group Health Research Institute, Seattle; Thomas E. Elliott, MD, of the Essentia Institute of Rural Health, Duluth, Minn.; Lynn DeBar, PhD, of the Kaiser Permanente Center for Health Research, Portland, Ore.; Ameena Ahmed, MD, MPH, and David Fisher, MD, of the Permanente Medical Group, San Francisco; Pamala A. Pawloski, PharmD, of the HealthPartners Institute for Education and Research, Minneapolis; and W. Troy Donahoo, MD, of the Colorado Permanente Medical Group, Denver.About the Kaiser Permanente Colorado Institute for Health Research
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences