Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Building blocks for new medications: the University of Graz is seeking a technology partner

19.03.2019

Painkillers and cancer medications, psychotherapeutic drugs, allergy medications – many substances used in the medical sciences are manufactured with the help of piperidin-4-ones. These are intermediates created by reactions with derivatives of ammonia. Werner Seebacher from the Institute of Pharmaceutical Sciences at the University of Graz has discovered an alternative reaction pathway to synthesise new kinds of piperidin-4-ones that have the potential to significantly increase the range of therapeutic options they offer. The University of Graz is currently looking for a partner from the pharmaceutical industry to realise the potential of this technology.

The opiod fentanyl, which is used in anaesthesia and in the treatment of acute and chronic pain, is one of the most important drugs made with piperidin-4-ones. However, these intermediates are also essential for the manufacture of numerous other drugs with a wide range of medical applications.


Werner Seebacher, University of Graz

Photo: University of Graz/Tzivanopoulos

“The synthesis technology we have developed gives us access to variants of piperidin-4-ones that cannot be obtained using traditional reaction pathways”, explains Werner Seebacher.

“What is special about our piperidin-4-ones is that they can be further modified as required. This opens up a range of new therapeutic possibilities”, says Seebacher, emphasising the significance of this technology, for which a European patent is now pending.

Further research is needed to discover exactly what those possibilities are. The University of Graz is currently looking for an industrial partner to produce these promising molecular components on a large scale and to press ahead with their development into new substances.

For further details see
https://static.uni-graz.at/fileadmin/forschen/dokumente/technologietransfer/Tech...

Wissenschaftliche Ansprechpartner:

Priv.-Doz. Dr. Werner Seebacher
Institute of Pharmaceutical Sciences, University of Graz
Tel.: +43 (0)316 380-5383; 8648
E-mail: w.seebacher@uni-graz.at

Mag. Gudrun Pichler | idw - Informationsdienst Wissenschaft
Further information:
https://www.uni-graz.at

Further reports about: chronic pain drugs medical applications molecular components synthesis

More articles from Health and Medicine:

nachricht Deep stimulation improves cognitive control by augmenting brain rhythms
04.04.2019 | Picower Institute at MIT

nachricht Black nanoparticles slow the growth of tumors
04.04.2019 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explosion on Jupiter-sized star 10 times more powerful than ever seen on our sun

A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter

  • Coolest and smallest star to produce a superflare found
  • Star is a tenth of the radius of our Sun
  • Researchers led by University of Warwick could only see...

Im Focus: Quantum simulation more stable than expected

A localization phenomenon boosts the accuracy of solving quantum many-body problems with quantum computers which are otherwise challenging for conventional computers. This brings such digital quantum simulation within reach on quantum devices available today.

Quantum computers promise to solve certain computational problems exponentially faster than any classical machine. “A particularly promising application is the...

Im Focus: Largest, fastest array of microscopic 'traffic cops' for optical communications

The technology could revolutionize how information travels through data centers and artificial intelligence networks

Engineers at the University of California, Berkeley have built a new photonic switch that can control the direction of light passing through optical fibers...

Im Focus: A long-distance relationship in femtoseconds

Physicists observe how electron-hole pairs drift apart at ultrafast speed, but still remain strongly bound.

Modern electronics relies on ultrafast charge motion on ever shorter length scales. Physicists from Regensburg and Gothenburg have now succeeded in resolving a...

Im Focus: Researchers 3D print metamaterials with novel optical properties

Engineers create novel optical devices, including a moth eye-inspired omnidirectional microwave antenna

A team of engineers at Tufts University has developed a series of 3D printed metamaterials with unique microwave or optical properties that go beyond what is...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

Fraunhofer FHR at the IEEE Radar Conference 2019 in Boston, USA

09.04.2019 | Event News

 
Latest News

New automated biological-sample analysis systems to accelerate disease detection

18.04.2019 | Life Sciences

Explosion on Jupiter-sized star 10 times more powerful than ever seen on our sun

18.04.2019 | Physics and Astronomy

New eDNA technology used to quickly assess coral reefs

18.04.2019 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>